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This chapter discusses various substances and therapies for dermatological applications, including heliotherapy, UVB, khellin, and others, but reports no new research findings.

This article discusses scalp micropigmentation as a noninvasive method to conceal various forms of hair loss and scalp abnormalities and reports no clinical results; the authors highlight its safe and effective application.

In this report, a 65-year-old Omani male undergoing cyclosporine A treatment experienced hair repigmentation as a rare side effect.

This systematic review and meta-analysis found that bimatoprost, especially when used with NB-UVB phototherapy, FxCO2 laser, or mometasone, may be an effective and well-tolerated treatment option for vitiligo, achieving significant patient satisfaction and repigmentation, despite some limitations like small sample sizes and high costs.

This case report details the lack of confluent repigmentation in an 8-year-old girl with vitiligo after three years of trioxsalen and ultraviolet light treatment.

This study found that intradermal injections of autologous cell-free fat extract significantly improved the condition of postinflammatory hyperpigmentation patients, with high patient satisfaction and minimal adverse effects.

This study found that scalp micropigmentation improved esthetic outcomes and patient satisfaction in scarring alopecia, particularly in conditions with less fibrosis like frontal fibrosing alopecia and traction alopecia.

Scalp micropigmentation is a process where tiny dots of pigment are tattooed onto the scalp to create the appearance of a shaved head or fuller hair.

This review discusses how permanent micropigmentation can restore eyebrow appearance and potentially improve psychosocial well-being in cancer survivors experiencing alopecia after chemotherapy, but it reports no new clinical results.

In this study, using a 1064 nm picosecond Nd:YAG laser effectively removed undesirable scalp micropigmentation in four patients within 1–3 treatment sessions, with no unexpected adverse events reported.

The abstract reports that non-cultured cellular grafting has become a prevalent and cost-effective method for treating stable vitiligo, with safety and effectiveness confirmed by two decades of studies. It critiques strict legislative oversight, suggesting it might unnecessarily increase costs and limit patient access.

This study reported that gain-of-function mutations in TRPV3 lead to hair loss in mice by disrupting inner root sheath keratinocyte differentiation, ultimately causing follicular keratinocyte stem cell exhaustion and permanent follicle disruption.

In this review, microneedling and platelet-rich plasma were identified as safe and effective cosmetic procedures for diverse skin types, especially among individuals with skin of color, due to their lower risk of postinflammatory hyperpigmentation and faster recovery compared to laser treatments.

Minoxidil 5% caused skin discoloration in a man using it for hair loss.

This review discusses surgical treatments for vitiligo, emphasizing the importance of proper preparation of the recipient site to improve cosmetic outcomes, while highlighting ongoing research and trials.

In this study, micropigmentation was reported to be an effective method for camouflaging hair loss and scalp scars in Korean patients, with high satisfaction in 42 out of 43 cases.

This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.

This study found that human iPSC-derived melanocytes from vitiligo patients successfully integrated into mouse hair follicles and epidermis, demonstrating potential for personalized therapy for depigmentation.

In this study, researchers discovered two new signaling pathways that regulate how melanocytes establish pigment patterns in reconstituted hair-bearing skin, offering insights that could inform strategies to prevent hair greying.

PRP treatment improved skin pigmentation and appearance in facial lichen planus pigmentosus.

This study concluded that controlled micro-injury induces hair regeneration and vitiligo repigmentation in mice, potentially through the Wnt/β-catenin pathway.

This case study reports on a 72-year-old woman with frontal fibrosing alopecia and hair repigmentation, suggesting the rare occurrence of canities reversal could aid in diagnosing FFA.

This study reports that the side population technique can isolate melanocyte stem cells from human hair follicles, potentially allowing them to be used for skin pigmentation repopulation.

This case report describes repigmentation and curling of hair in a patient undergoing acitretin therapy.

Intradermal PRP significantly improved melasma in dark skin, with lasting results and no relapse after 3 months.

This study found that sebaceous glands can regenerate after PPARg deletion in adult skin, relying on the hair cycle and FGFR signaling.

This review found that platelet-rich plasma shows potential in improving melasma, though its overall benefit varies across different treatment methods and may not enhance results when combined with certain other treatments.

In a randomized phase 2b clinical trial, oral ritlecitinib significantly reduced facial vitiligo area scores in patients with active nonsegmental vitiligo compared to placebo, with a favorable safety profile observed over 48 weeks, suggesting its potential as an effective treatment option (Ezzedine et al., 2023).