The Efficacy of Platelet-Rich Plasma in Facial Lichen Planus Pigmentosus: A Prospective Pilot Study

This prospective pilot study evaluated the efficacy of platelet-rich plasma (PRP) for treating facial lichen planus pigmentosus (LPP) in 12 patients. Over 12 weeks, intradermal PRP injections led to a significant reduction in melanin index, indicating decreased pigmentation, with dermatologists' assessments and patient satisfaction scores supporting these results. Most patients reported moderate to good improvement, and adverse effects were minimal. The study concluded that PRP is a promising treatment for LPP, offering a potential alternative to existing therapies, though further research with larger sample sizes and longer follow-up is necessary to confirm these findings.