August 2022 in “Journal of Cosmetic Dermatology” This article reviews scalp micropigmentation techniques for camouflaging scalp scars and alopecia, emphasizing the principles and skills required to achieve a natural appearance, but it reports no new clinical results.
This study found that transgenic expression of Endothelin 3 in mice can maintain a dark pigmentation phenotype independently of Mc1r signaling by regulating melanogenic genes.
1 citations
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January 2014 in “Aesthetic Plastic Surgery” Tattooing improves appearance of scalp alopecia and scars.
January 2026 in “SKIN The Journal of Cutaneous Medicine” Rituximab treatment led to complete hair regrowth and improved skin in a woman with pemphigus foliaceus.
April 2018 in “Journal of Investigative Dermatology” This study investigated novel genetic tools to manipulate hair follicle compartments in mice and found that altering dermal papilla genes can significantly impact hair pigmentation.
2 citations
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September 2023 in “PubMed” The studies reviewed found favorable treatment outcomes for hypopigmented scars using PGF2α agonists with no adverse events reported. However, the authors highlight the need for larger randomized controlled trials to better understand their effectiveness and long-term safety.
15 citations
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January 2019 in “Experimental Dermatology” In this study, full-thickness wounding on Lanyu pigs led to scar formation and disrupted cell markers, while partial-thickness wounding allowed limited regeneration of rete ridges and papillary dermis.
3 citations
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June 2025 in “Stem Cell Research & Therapy” Hair follicle-derived melanocyte transplant could effectively treat vitiligo by restoring skin color.
24 citations
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March 2018 in “Pigment Cell & Melanoma Research” This review discusses the interactions between melanocyte stem cells and their niche in hair regeneration and repair, but reports no new results; recent studies on molecular pathways are highlighted.
7 citations
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March 1990 in “Pigment Cell Research” This animal study observed that while topical MBEH and intraperitoneal phenol induced hair graying in eumelanic mice, they had little effect on pheomelanic mice, and amcinonide reduced certain epidermal melanocytes in both.
1 citations
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July 2015 in “British Journal of Dermatology” Imiquimod improved skin pigmentation in most patients with xeroderma pigmentosum and may prevent further skin cancer, but some treatments can have side effects.
2 citations
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May 2023 in “Photobiomodulation, photomedicine, and laser surgery” This editorial reviews how photobiomodulation therapy might effectively treat both hyperpigmentation and depigmentation skin disorders, but reports no new clinical results.
August 2023 in “Portuguese journal of dermatology and venereology” Cyclosporine can reverse hair graying.
10 citations
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September 1994 in “International Journal of Dermatology” This case report describes three Iranian men with gradual reddish-brown pigmentation on their cheeks and preauricular areas since childhood, unresponsive to sunblocks and topical steroids.
41 citations
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December 2018 in “Experimental Dermatology” This review explores recent findings on the roles of melanocyte and melanocyte stem cells in the hair follicle, highlighting their importance for skin health and potential applications in regenerative medicine, but reports no new clinical results.
October 2007 in “Journal of Investigative Dermatology” The document suggests a bacteria plays a significant role in acne rosacea and that white hair can regain color after transplant, meriting more research on reversing grey hair.
7 citations
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January 2008 in “Indian Journal of Dermatology” This review discusses the clinical manifestations and genetic basis of pigmentary mosaicism, highlighting its varied phenotypic expressions, but reports no new clinical results.
1 citations
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January 2018 in “Methods in molecular biology” This research describes methods to activate melanocyte stem cells during hair follicle regeneration and to isolate melanocytes from neonatal mouse skin, with the aim of studying melanogenesis for potential clinical applications.
9 citations
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September 2020 in “Journal of cosmetic dermatology” This case report describes koebnerization-induced vitiligo in a woman following repeated eyebrow microblading, suggesting a link between the procedure and the phenomenon in susceptible individuals.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers observed that vitiligo-affected skin shows a selective depletion of NTRK2+ melanocyte subpopulations with progenitor features, which may contribute to poor treatment responses.
1 citations
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May 2016 in “Journal of Cosmetic Dermatology” This study found that the expression of CK 15 and CK 19 in vitiligo patients undergoing phototherapy was correlated with improved repigmentation, suggesting their potential as markers for stem cell stimulation.
July 2026 in “Indian Journal of Dermatology Venereology and Leprology”
April 2018 in “Journal of Investigative Dermatology” This study found that BMP signaling is involved in regulating melanogenesis, pigment transfer, and melanocyte migration, contributing to our understanding of skin pigmentation mechanisms.
2 citations
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August 2025 in “Reports — Medical Cases Images and Videos” In this case report, a rare melanotrichoblastoma tumor was identified in a 51-year-old female following the histological and immunohistochemical analysis of a lesion on the pubo-inguinal area, presenting with strong epithelial marker positivity and a low proliferative index.
December 2025 in “Dermatology Reports” This source describes vitiligo as a chronic condition marked by the loss of skin pigmentation and discusses leukotrichia, a feature affecting 10% to 60% of cases, which arises from melanocyte loss in hair follicles and appears as well-defined white patches on the skin.
This article discusses trichopigmentation as an innovative, reversible treatment for hair loss in both males and females, but it does not report new clinical results.
7 citations
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March 2023 in “Lasers in Surgery and Medicine” This study found that a single ablative fractional laser treatment significantly reduced hedgehog pathway gene expression in microscopic murine basal cell carcinomas, nearly matching the effects of repeated topical vismodegib applications.
6 citations
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September 2017 in “Experimental and Therapeutic Medicine” This study found that two short peptides derived from pigment epithelium-derived factor significantly accelerated full-thickness skin wound healing in mice through mechanisms that may involve increased cell proliferation and stem cell mobilization.
11 citations
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August 1987 in “Archives of Dermatology” In this study, researchers found that Langerhans' cells likely do not play a role in the depigmentation process in C57Bl/Ler-vit.vit mice, as their number was normal during depigmentation and highest afterward.
October 2023 in “European journal of dermatology/EJD. European journal of dermatology” In this study, I-PRF, a blood-derived biomaterial without anticoagulants, was found to inhibit melanin production and reduce oxidative stress damage in a rat model of melasma, suggesting it as a safe and cost-effective treatment option.