Hair Follicle-Derived Melanocyte Transplant as a Promising Treatment Strategy for Vitiligo

    June 2025 in “ Stem Cell Research & Therapy ”
    Ran Fan, Jie Gao, Jin Chen
    Studysummary Hair follicle-derived melanocyte transplant could effectively treat vitiligo by restoring skin color.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 9

    1. Hair Regrowth in Alopecia Areata and Re-Pigmentation in Vitiligo in Response to Treatment: Commonalities and Differences Journal of the European Academy of Dermatology and Venereology · 2024
    2. Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences International journal of molecular sciences · 2024
    3. A Mouse Model of Vitiligo Based on Endogenous Auto-Reactive CD8+ T Cell Targeting Skin Melanocyte Cell Regeneration · 2022
    4. A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells Stem Cell Research & Therapy · 2021
    5. Hyperactivation of Sympathetic Nerves Drives Depletion of Melanocyte Stem Cells Nature · 2020
    6. Harnessing the Power of Regenerative Therapy for Vitiligo and Alopecia Areata ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2019
    7. Therapeutic Potential of Patient iPSC-Derived Melanocytes in Autologous Transplantation Cell reports · 2019
    8. Mechanisms of Repigmentation Induced by Photobiomodulation Therapy in Vitiligo Experimental dermatology · 2019
    9. Quality of Life, Burden of Disease, Comorbidities, and Systemic Effects in Vitiligo Patients Dermatologic clinics · 2017

    Related research 4

    1. Casein Kinase 1 Inhibition in Keratinocytes Enhances the Migration of Melanocyte Precursors in the Hair Follicle via KitL/c-Kit Signaling Pathway Journal of Investigative Dermatology · 2023
    2. Melanocyte Stem Cells: A Melanocyte Reservoir in Hair Follicles for Hair and Skin Pigmentation Pigment Cell & Melanoma Research · 2011
    3. Functionally Distinct Melanocyte Populations Revealed by Reconstitution of Hair Follicles in Mice Pigment Cell & Melanoma Research · 2010
    4. Aging of the Hair Follicle Pigmentation System International journal of trichology · 2009