A Mouse Model of Vitiligo Based on Endogenous Auto-Reactive CD8+ T Cell Targeting Skin Melanocyte

    October 2022 in “ Cell Regeneration ”
    Daoming Chen, Zijian Xu, Jun Cui, Ting Chen
    Studysummary This study describes a new mouse model for vitiligo that mimics key clinical features such as skin depigmentation and CD8 + T cell infiltration, providing a useful tool for in-depth research and drug discovery.
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    Research cited in this study 2

    1. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration Cell Stem Cell · 2018
    2. Concomitant Vitiligo and Psoriasis in a Patient Treated with Interferon Alfa-2a for Chronic Hepatitis B Infection Pediatric Dermatology · 2004