Concomitant Vitiligo and Psoriasis in a Patient Treated with Interferon Alfa-2a for Chronic Hepatitis B Infection

    September 2004 in “ Pediatric Dermatology ”
    Deniz Seçkin, Çiçek Durusoy, Sedef Şahin
    TLDR A girl developed vitiligo and psoriasis after hepatitis B treatment, and stopping the treatment didn't help.
    The document reported a case of a 10-year-old girl with chronic hepatitis B who developed both vitiligo and psoriasis after being treated with interferon alfa-2a. These skin conditions did not improve even after the interferon treatment was stopped. This was notable because the simultaneous occurrence of vitiligo and psoriasis as a side effect of interferon alfa-2a had not been previously documented. The study highlighted the potent immunomodulatory effects of interferon alfa-2a, which can trigger autoimmune diseases in susceptible individuals.
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