TLDR Pigmentary mosaicism causes skin color changes and can affect multiple body systems, but has no cure.
Pigmentary mosaicism was characterized by skin manifestations of hypo- or hyperpigmented lesions along Blaschko's lines, often due to chromosomal mosaicism. This condition could involve multiple systems, with phenotypic expressions in the dermal and musculoskeletal systems, and was sometimes familial. It included hair abnormalities like alopecia, nail and dental changes, eye abnormalities, joint and skeletal issues, mental retardation, seizures, and cardiac, renal, and genital defects. Diagnosis could be challenging due to similarities with other conditions, and no definitive treatment existed, though systemic examinations and management of symptoms like seizures were recommended.
September 2009 in “Pediatric Dermatology” UVB is good for a skin condition in Asian kids, a lotion works for head lice, a drug helps with a skin blistering disorder, a foam reduces itchiness in skin inflammation, birthmarks can be more widespread, and criteria for a neurocutaneous disorder were agreed upon.
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July 2010 in “British Journal of Dermatology” The document suggests a rare skin condition might be caused by a genetic phenomenon.
June 2008 in “Springer eBooks” The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."
59 citations
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June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
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December 2019 in “The Open Dermatology Journal” Linear Discoid Lupus Erythematosus of the scalp can cause hair loss and should be considered in similar cases.
