January 2013 in “Psychiatry and clinical neurosciences” This case report emphasizes the importance of investigating physical symptoms in patients with depression, as persistent loss of libido in this patient led to the diagnosis of craniopharyngioma.
April 2017 in “Australasian Journal of Dermatology” This study observed that systemic acitretin improved symptoms in 75% of lichen planopilaris patients, despite varied responses and a dominant female prevalence.
56 citations
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December 1978 in “The Journal of Dermatologic Surgery and Oncology” This study reported successful and cosmetically acceptable repigmentation of leukoderma in three patients using minigrafts of normally pigmented, autologous skin.
This article discusses localized repigmentation of hair, suggesting it may be an indicator of underlying melanoma, and emphasizes the need for careful diagnostic evaluation.
May 2024 in “Cardiometry” This study documented that after hair transplantation, 34 patients with white or gray hair in the donor area experienced color repigmentation, with most regaining their original blackish color in the recipient area over a 1-year follow-up.
6 citations
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October 2006 Understanding repigmentation mechanisms in vitiligo can improve treatments and patient outcomes.
24 citations
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September 2008 in “Clinical and experimental dermatology” Repigmentation in vitiligo may come from melanocyte stem cells in the skin.
15 citations
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January 2013 in “Dermatologic Surgery” This study observed that white hair follicles in vitiligo patients may repigment following epithelial grafting and phototherapy, suggesting potential cosmetic improvements in vitiligo treatment.
38 citations
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February 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This report describes two cases of sustained hair repigmentation related to porphyria cutanea tarda, though the underlying mechanism remains unclear.
August 2026 in “Journal of Personalized Medicine” This narrative review proposes the concept of "repigmentation competence" for vitiligo lesions, suggesting that therapy responses are influenced by lesion-specific biological factors related to immune, regenerative, regulatory, and microenvironmental processes, and highlights the emerging role of combination therapies targeting these pathways.
60 citations
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April 2006 in “International Journal of Dermatology” This review discusses various surgical techniques for vitiligo repigmentation, noting that suction blister and split-thickness skin grafting have the highest success rates according to previous analysis, but reports no new results.
January 2022 in “Skin appendage disorders” This case report describes a unique occurrence of alopecia totalis resulting in pigmented hair growth over superficial scalp veins in an adult female using augmented betamethasone dipropionate ointment.
2 citations
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March 2023 in “JAAD case reports” This case report describes the unexpected hair repigmentation surrounding a scalp tumor in a 74-year-old man, suggesting a potential link between the carcinoma and changes in hair pigmentation.
July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study by Refat et al. found that the level of CD8+ T cell infiltrates in vitiligo lesions before surgical treatment can predict the likelihood of successful repigmentation, suggesting a potential new method for identifying patients who may benefit the most from surgical interventions.
9 citations
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November 2015 in “JAMA dermatology” This case study describes an elderly woman with distinctive black hair patches and scalp pigmentation, but it does not provide a diagnosis or new findings.
2 citations
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September 2020 in “International journal of radiology & radiation therapy” This study describes changes in scalp hair color, including rare instances of repigmentation, following volumetric modulated arc therapy for skin cancer; this potential side effect may warrant discussion during informed consent.
17 citations
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January 2015 in “Dermatology online journal” This report describes a patient experiencing hair repigmentation linked to adalimumab therapy, a TNF inhibitor, a phenomenon not previously associated with this class of drugs.
37 citations
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October 2017 in “Advanced drug delivery reviews” This review explores the mechanisms of skin repigmentation and therapeutic strategies for pigmentation disorders following burn injuries, but it presents no new clinical results.
9 citations
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December 2010 in “Journal of The European Academy of Dermatology and Venereology” This letter reports repigmentation of hair in patients receiving latanoprost therapy.
1 citations
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March 2025 in “Journal of Cosmetic Dermatology” This case report describes promising results in treating poliosis circumscripta with exosomes and fractional picosecond laser, showing significant hair regrowth and repigmentation, though spontaneous repigmentation cannot be ruled out.
28 citations
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December 2019 in “Skin appendage disorders” This review discusses medication-induced gray hair repigmentation, highlighting that certain anti-inflammatory drugs and melanogenesis stimulators can cause diffuse repigmentation, though evidence remains low-quality and these medications are not currently indicated for this purpose.
June 2026 in “Journal of Investigative Dermatology” This study found that certain proteins linked to immune suppression and melanogenesis are associated with repigmentation in vitiligo patients undergoing standard treatment, suggesting these proteins and their pathways play roles distinct from merely reversing skin lesions.
November 2023 in “Journal of the American Academy of Dermatology” This study explored spontaneous repigmentation after phenol-croton oil peels in skin of color, finding that temporary hypopigmentation resolved by day 21 in both a black-skin domestic pig model and human clinical observations, highlighting potential for these procedures despite past concerns about pigmentation issues.
January 2025 in “Tanzania journal of health research/Tanzania Journal of Health Research” This research discusses autologous mini-punch grafting, a surgical technique for treating stable, minor vitiligo when non-surgical treatments fail, reporting up to 75% repigmentation success in 78% of treated patients, although complications like cobblestoning and graft rejection may occur.
39 citations
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August 2005 in “Dermatologic surgery” This review describes the expanding medical uses of micropigmentation, including for vitiligo, burn scars, and nipple-areola reconstruction, and highlights safety concerns related to sterilization practices.
17 citations
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December 2013 in “Dermatologic Surgery” This study found that autologous noncultured epidermal suspension transplantation improved leukotrichia in 88.1% of treated vitiligo lesions without significant adverse events.
119 citations
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May 1987 in “The Journal of Dermatologic Surgery and Oncology” This study found that pigmentation following sclerotherapy is likely caused by hemosiderin deposition from red blood cells rather than post-inflammatory hyperpigmentation, with most cases resolving spontaneously within 6–24 months.
1 citations
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December 2023 in “Skin Research and Technology” This study reported successful repigmentation of perioral vitiligo using upper hair follicle transplantation combined with a 308 nm excimer laser, without undesirable hair growth in the treated areas, offering a potential approach for treating vitiligo cases unresponsive to traditional melanocyte transplantation.
23 citations
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April 2002 in “Journal of the American Academy of Dermatology” This case report describes persistent depigmented hair regrowth from an alopecia areata patch, challenging the previous assumption that such regrowth is only temporary.
41 citations
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April 2019 in “PLOS genetics” This study found that CD34- melanocyte stem cells regenerated pigmentation more efficiently, while CD34+ cells showed potential for neuron myelination, suggesting different therapeutic applications for each population.