8 citations
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January 2017 in “Korean Journal of Physiology and Pharmacology” This study found that pimecrolimus enhances melanin synthesis and promotes melanocyte migration, possibly by increasing MITF protein expression, which may explain its effectiveness in repigmenting vitiligo.
16 citations
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July 2016 in “Journal of Dermatological Science” This study found that stable regeneration of pigmented hairs in mice after severe wounding can occur when the wound is made during the anagen stage, influenced by Wnt and Kit signaling pathways.
This case report describes perifollicular melanocyte regeneration in the affected skin of a patient with bullous pemphigoid, highlighting an underreported aspect of the condition in skin of color patients, and emphasizing the need for increased awareness and earlier diagnosis in this demographic.
41 citations
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January 2006 in “Dermatology” This study found that noncultured epidermal cell transplantation is promising for treating stable vitiligo, achieving significant repigmentation and patient satisfaction based on objective and subjective evaluations.
11 citations
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January 2011 in “Journal of Cutaneous and Aesthetic Surgery” This study on a 30-year-old male reported that single-hair follicular unit transplant effectively repigmented a stable vitiligo patch, achieving complete pigmentation in 8 weeks with no recurrence after 6 months.
2 citations
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October 2018 in “Journal of Mind and Medical Sciences” In this study, researchers developed and validated a method to quantify pyrrolizidine alkaloids in honey and flour, increasing alkaloid recovery rates through successive extractions, achieving up to 86% recovery for honey and 76% for flour.
January 2023 in “Indian Dermatology Online Journal” This article reviews the indications for micropigmentation in dermatological conditions like stable vitiligo and alopecia, but presents no new clinical results.
20 citations
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February 2001 in “Dermatologic Surgery” This study reports that micropigmentation with iron oxide pigments is a safe and effective method for camouflaging scalp scars.
21 citations
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February 2017 in “Dermatologic surgery” In this study, different donor and recipient site preparation techniques for melanocyte-keratinocyte suspension were associated with similar repigmentation outcomes in stable vitiligo, but efficacy varied by body site.
This pilot study employed in-vivo multiphoton microscopy to visualize pigment-producing melanocytes in vitiligo patients, aiming to enhance understanding of treatment impacts and potentially improve transplantation therapies.
March 2008 in “Journal of Clinical Dermatology” In this study, micropigmentation of scalp and eyebrow scars showed satisfying cosmetic outcomes in 94% of patients with no complications, as pigments remained stable in the superficial dermis after three weeks.
3 citations
,
May 2010 in “Archives of dermatology” This excerpt discusses website navigation and access details for JAMA Dermatology and reports no new research findings.
January 2008 in “대한피부과학회지” This study found that micropigmentation effectively improved the cosmetic appearance of scalp and eyebrow scars in 94% of patients, with the pigments remaining safely in the superficial dermis after one year.
March 2024 in “Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān/Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān./Zahedan journal of researches in medical sciences” This case study describes the successful treatment of facial pigmentation using microneedling combined with platelet-rich plasma, suggesting high effectiveness with minimal side effects in this application.
9 citations
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July 2016 in “The Journal of Dermatology” This letter to the editor discusses an observed case of hair repigmentation linked with etretinate therapy but reports no new research findings.
7 citations
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April 2020 in “Curēus” In this pilot study, both microneedling and CO2 laser combined with hair transplantation and nbUVB demonstrated potential for inducing repigmentation in refractory palmar-plantar vitiligo, though further research is needed to ascertain their relative efficacy.
November 2025 in “International Journal of Advanced Research” In this case report, PRP therapy led to almost complete clearance of hypopigmentation in a 28-year-old Caucasian female after laser hair removal, suggesting PRP could be a promising treatment option for various hypopigmentation conditions.
4 citations
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November 2020 in “Journal of Craniofacial Surgery” This study found that scalp micropigmentation minimized visible fading over time and led to high patient satisfaction in treating scalp pigmentation issues, with all participants willing to recommend the procedure.
9 citations
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January 2013 in “Journal of Cutaneous and Aesthetic Surgery” This case report observed complete repigmentation of a stable vitiligo patch with body hair transplantation in a 28-year-old man, with no recurrence after 3 months.
8 citations
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July 2001 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This review summarizes the historical and evolving treatments for vitiligo, highlighting that combining medical and surgical approaches may enhance repigmentation outcomes, though more research and new protocols are needed.
6 citations
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November 2011 in “Journal of Dermatological Science” A new gene mutation may allow some piebaldism patients to regain skin color in white patches.
69 citations
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April 1998 in “Journal of The American Academy of Dermatology” In this study, single hair grafting was reported to be an effective treatment for localized/segmental vitiligo, notably in hairy skin areas, with repigmentation observed in 82% of those cases.
1 citations
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December 2015 in “Journal of the Medical Sciences (Berkala Ilmu Kedokteran)” This review discusses transplantation of melanocyte stem cells for vitiligo treatment and reports no new clinical results; it suggests the procedure could be effective in reactivating melanocyte precursors for repigmentation.
June 2025 in “Clinical and Experimental Dermatology” This report describes a rare case where a 76-year-old man's grey scalp hair unexpectedly regained its original orange to brown color after he underwent radiotherapy for squamous cell carcinoma, suggesting possible implications involving hair follicle melanocytes and radiation effects.
177 citations
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November 2002 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, stable types of leucoderma such as segmental vitiligo and piebaldism showed 100% repigmentation after melanocyte transplantation, suggesting surgery as the preferred method for these conditions.
June 2026 in “The Journal of Cosmetic Medicine” This narrative review reports that scalp micropigmentation offers immediate cosmetic improvements in hair density appearance, but does not promote actual hair regrowth and results vary based on the operator's skill.
12 citations
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November 1945 in “Archives of dermatology” In this study, hair color changes in piebald rats after skin grafting suggest that such changes are more likely due to the surgical process than the new environment.
March 2026 in “European Journal of Biomedical and Life Sciences” This study highlights restorative dermopigmentation as a growing field in aesthetic medicine, aiming to address skin concerns like alopecia and age-related pigment loss by improving aesthetic and structural dermal deficits.
March 2026 in “Preprints.org” In this study, plerixafor was found to enhance melanogenesis and promote repigmentation by engaging a β-arrestin–β-catenin–MITF signaling axis in melanocytes, and showed effectiveness in restoring depigmentation in a murine model without causing systemic toxicity.
2 citations
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January 2023 in “International journal of biological sciences” This review discusses the mechanisms of hair repigmentation and reports no clinical results; the authors suggest further research into topical treatments for reversing gray hair.