What's New in the Treatment of Vitiligo

    July 2001 in “ JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology ”
    Rafael Falabella
    TLDR New treatments for vitiligo show promise but still face challenges, especially for hands and feet.
    The document reviewed the evolution of vitiligo treatments over the past 50 years, highlighting significant advancements such as the introduction of 8-methoxypsoralen with UVA, corticosteroids, and narrow-band UVB therapy. Melanocyte grafting and cultured pigment cell transplantation emerged as important tools for refractory cases. Recent innovations included pseudocatalase for neutralizing reactive molecules and precise surgical techniques for melanocyte transplantation. Despite these advancements, repigmentation rates remained around 70-75%, with certain areas like hands and feet being particularly challenging. The document suggested that combination therapies, integrating medical and surgical approaches, could improve outcomes. Future research should focus on understanding the pathogenesis of vitiligo and developing molecules to stimulate melanocyte division and migration, potentially transforming vitiligo into a stable condition with more effective repigmentation strategies.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community 8 months Oral min and Dutasteride

      in Progress Pictures  62 upvotes 2 days ago
      Oral minoxidil and dutasteride are used for hair loss with mixed results. Some users report new growth, while others suggest scalp inflammation may be an issue.

      community 8 weeks in with microneedling and minoxidil/tretinoin

      in Progress Pictures  65 upvotes 2 days ago
      The user is using a combination of microneedling, minoxidil, tretinoin, scalp massages, and red light therapy to address hair loss, with a focus on the hairline and temples. They emphasize the importance of scalp massages and have seen regrowth, attributing success to their comprehensive routine.

      community 8 Months of Crown Recovery on Treatment

      in Progress Pictures  44 upvotes 5 days ago
      The user shared progress pictures showing crown recovery after 8 months of using 1mg finasteride, 2mg minoxidil, and 2% ketoconazole shampoo. They noted significant hair texture changes and are hopeful for temple recovery.

      community 8 months apart with finasteride and Minoxidil

      in Progress Pictures  425 upvotes 6 days ago
      The user shared progress pictures showing significant hair regrowth after 8 months using finasteride and Minoxidil foam. They have not used microneedling and are considering oral Minoxidil but currently use topical Minoxidil and oral finasteride.

      community 8 months on oral minoxidil. No sign of regrowth.

      in Minoxidil  14 upvotes 1 week ago
      The user has been taking 2mg oral minoxidil and 1mg finasteride but has seen no hair regrowth after 8 months, leading to concerns about being a non-responder. They are considering increasing the minoxidil dosage or switching to dutasteride, while also using keto shampoo and microneedling, but remain skeptical about the effectiveness of minoxidil.

      community 8 months results (dut 0.5 and min 2.5)

      in Progress Pictures  20 upvotes 3 weeks ago
      A user shared their 8-month progress using dutasteride 0.5 mg and oral minoxidil 2.5 mg for hair loss, expressing disappointment with the results and considering increasing the dosage. Other users advised patience, suggesting that improvements can continue over time, and recommended consulting a dermatologist before making changes.

    Similar Research

    5 / 1000+ results