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This study observed an unexpected case where a 44-year-old woman developed linear scalp pigmentation, resembling a tattoo, after undergoing a microneedling procedure followed by hair dyeing two days later, emphasizing the need to advise patients on avoiding hair dye application soon after such treatments.

In this study, researchers treated 20 patients with lip vitiligo using manual needling followed by 88% phenol application and found that 65% of patients achieved more than 75% repigmentation within three months, indicating this combination as an effective treatment option.

This study examined the use of medical dermapigmentation to restore lip appearance after traumatic injuries, finding that a staged approach effectively camouflages scar tissue, enhances symmetry, and improves psychological well-being, demonstrating benefits in a clinical case of a dog bite.

This review discusses the widespread acceptance of micropigmentation for cosmetic purposes and its various medical applications, but reports no new clinical findings.

This study reported successful repigmentation without scarring in patients with localized and segmental vitiligo after epidermal grafting, but the Koebner phenomenon hindered similar results in some with generalized vitiligo.

This study found that none of the depigmenting compounds tested in beef heifers produced a permanent depigmenting effect, though visible depigmentation lasted up to 3 months.

In this study on a mouse model of vitiligo, NB-UVB/ADSC combination therapy improved oxidative stress and calcium homeostasis, but the protective effect was reversed by inhibiting Nr2 signaling.

New treatments and drugs show promise for improving skin pigmentation and regeneration.

Regenerative medicine is effective and safe for treating vitiligo.

This systematic review examined 64 randomized controlled clinical trials on regenerative medicine for specific dermatologic disorders, reporting up to 68.4% improvement in androgenetic alopecia and up to 71% improvement in vitiligo among 2888 patients.

Postinflammatory hyperpigmentation causes dark skin patches and needs personalized treatment.

In this study, a combined technique of mini-punch grafting and follicular hair transplant was used on five patients with stable hairline vitiligo, resulting in satisfactory repigmentation and hair regrowth within the hairline while preventing hair loss and achieving repigmentation outside it.

This article discusses the potential use of platelet-rich plasma as a treatment for vitiligo, but reports no new clinical results; further investigation is needed.

Anti-PD-L1 immunotherapy can cause hair loss and unexpected hair color change, but treatment can restore hair growth and color.

This study suggests that a purified sphingolipid fraction can activate melanocyte stem cells via p38 signalling, potentially offering a non-UV-based treatment for vitiligo, though additional validation is needed.

This study found that applying 5% topical minoxidil gel on treatment-resistant vitiligo patches may promote early repigmentation, showing significant improvement at one month compared to a placebo, though later differences were not statistically significant.

In this case study, a patient experienced darkening of hair color after taking acitretin, an oral retinoid known for potentially causing alopecia, marking a rare and undocumented phenomenon.

This study found that scalp micropigmentation was a safe and effective cosmetic solution for localized alopecia, showing significant improvement in visual density and high patient satisfaction without adverse events.

This study discusses the safety, complications, and limitations of melanocyte transplantation for treating vitiligo, noting that these techniques are generally safe and often combined with medical treatments for repigmenting stable vitiligo macules.

In this study, researchers found that in adult mice, new hair follicles with pigmentation can regenerate from the epidermis after skin wounding, aided by melanocyte stem cells moving from nearby existing hair follicles.

This study highlighted the need for more extensive research, ideally randomized controlled trials with larger patient groups, to determine the effect of the indicated treatment on hair repigmentation following AA.

This study reports no known changes in hair pigmentation associated with brentuximab vedotin, despite its various other documented adverse effects.

This review discusses scalp micropigmentation techniques and their customization to individual patients, but reports no new clinical results.

This study found that exosome-based therapy using rose stem cell-derived exosomes may safely induce hair repigmentation in individuals with gray hair, particularly for those with shorter durations of graying and androgenetic alopecia.

This review discusses various techniques for depigmentation in vitiligo patients and suggests that cryotherapy, performed by an experienced professional, may be the most cost-effective and accessible method.

This study found that the patchwork mutation in mice affects melanocyte survival in hair follicles, leading to a variegated coat pattern without partially pigmented hairs due to a community effect among melanoblasts.

This article contains no new research findings or results.

This study found that a combination of low-fluence Q-switched 1064 nm Nd:YAG laser, hydroquinone cream, and oral tranexamic acid showed promising results for Riehl’s melanosis in Asian patients, with no serious adverse events reported.

This review presents clinical and preclinical evidence supporting innovative regenerative approaches to treat vitiligo, as existing treatments lack a specific cure and predictable long-term repigmentation outcomes.