Scalp Hair Repigmentation After Radiotherapy

June 2025 in “ Clinical and Experimental Dermatology ”

Andrew Maxwell, Christopher Chew, Ian Porter, Rodney Sinclair, Adam T Sheridan

scalp hair repigmentation radiotherapy squamous cell carcinoma alopecia hair follicle melanocytes melanocyte stem cell plasticity

TLDR A 76-year-old man's grey hair turned back to its original color after radiotherapy.

A 76-year-old male experienced unexpected scalp hair repigmentation after receiving radiotherapy for squamous cell carcinoma. Initially having grey hair for over 10 years, the patient underwent 45 Gy of radiotherapy in 25 fractions, which led to temporary alopecia. Upon hair regrowth four months later, his hair returned to its youthful orange-brown color. This rare case contributes to the limited literature on hair repigmentation post-radiotherapy, suggesting that hair follicle melanocytes and melanocyte stem cell plasticity may play a role in hair color restoration, influenced by factors such as radiation.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 8 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community 1 1/2 Year Results on Finasteride

in Finasteride 185 upvotes 6 years ago

A user sharing their positive experience with taking finasteride as part of their hair loss treatment regimen, which also included biotin, Nizoral Shampoo, OGX Biotin & Collagen Shampoo, and iRestore Laser Cap. Others shared their own experiences and advice on treating hair loss.

community The Virgin Scalp Hair vs. The Chad Facial Hair

in Satire 147 upvotes 4 years ago

Comparing scalp hair to facial hair, and the effects of DHT on growth. Possible treatments discussed include Minoxidil, finasteride and RU58841.

community What do these pictures say about my hair and scalp if anything? Miniaturization, inflammation, etc.?

in Research/Science 74 upvotes 2 years ago

Hair loss and scalp issues, with people discussing possible treatments such as Nizoral shampoo, Minoxidil, neem oil, and finasteride.

community How come beard hair on minoxidil is permanent while scalp hair while on it under fin/duta is not?

in Minoxidil 50 upvotes 4 months ago

Beard hair grown with minoxidil can become permanent because it is not sensitive to DHT, unlike scalp hair, which requires ongoing minoxidil use even with DHT blockers like finasteride or dutasteride. Dutasteride reduces scalp DHT significantly but not completely, which may explain why scalp hair still needs minoxidil for maintenance.

community Estrogen is an anabolic for scalp hair, if you mix it with growth stimulants such as oral minoxidil. All we need is an artificial SARM-estrogen that will work only with hair and will be invisible for the rest of the body + some next level AA only for hair – goodbye hair transplant industry

in Transgender 137 upvotes 3 years ago

Hair loss discussion mentions using estrogen mixed with growth stimulants like oral minoxidil for scalp hair growth. Idea proposed for an artificial SARM-estrogen that only affects hair without body side effects.

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