Pimecrolimus Increases the Melanogenesis and Migration of Melanocytes In Vitro

    January 2017 in “ Korean Journal of Physiology and Pharmacology ”
    Ping Xu, Jie Chen, Cheng Tan, Ren-Sheng Lai, Zhong-Sheng Min
    TLDR Pimecrolimus boosts melanin production and movement of skin pigment cells.
    The document discussed the effects of pimecrolimus on melanogenesis and the migration of melanocytes in vitro. It was found that pimecrolimus increased both the production of melanin and the movement of melanocytes, which are critical processes in skin pigmentation. This research provided insights into potential therapeutic applications for conditions like vitiligo, where repigmentation is desired. The study was conducted in a controlled laboratory setting, focusing on cellular responses rather than involving human participants directly.
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