Repigmentation of Hair After Latanoprost Therapy

    December 2010 in “ Journal of The European Academy of Dermatology and Venereology ”
    Silvano Bellandi, L. Amato, E. M. Cipollini, Emiliano Antiga, L. Brandini, Paolo Fabbri
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    TLDR Latanoprost therapy potentially caused a woman's white hair to darken again.
    In 2011, a 65-year-old woman with open-angle glaucoma experienced repigmentation of her white hair after using latanoprost therapy. She noticed her hair gradually darkening about 3 years after starting the therapy, a process that took about a year, starting from the root and spreading to the entire length of the hair. She did not use any hair dye, new shampoo, or scalp lotion during this time. The mechanism behind latanoprost-associated hair and skin changes in growth and pigmentation is not well understood, but it's likely mediated by the PGF2a receptor, which latanoprost selectively targets. This case suggested that hair greying might not be irreversible and that latanoprost therapy could potentially cause hair repigmentation.
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      community Why not Travopost? More effective than min, and stackable.

      in Research/Science  17 upvotes 3 months ago
      Travoprost may be more effective than minoxidil for hair growth and can be used alongside it, but its effectiveness is debated due to inconsistent dosing results. Travoprost is expensive and not widely used, with alternatives like latanoprost and bimatoprost being more accessible.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  57 upvotes 1 week ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 month ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Painkillers May Block Minoxidil

      in Research/Science  15 upvotes 1 week ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

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