9 citations
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November 2017 in “Journal of Glaucoma” This case report documents a patient experiencing paradoxical depigmentation of the periocular skin after one year of using latanoprost, a finding not previously associated with this medication.
216 citations
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October 1997 in “American Journal of Ophthalmology” This study found that unilateral topical latanoprost use for glaucoma was associated with hypertrichosis and increased pigmentation of eyelashes in the treated eye compared to the untreated eye.
39 citations
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April 2001 in “Journal of The American Academy of Dermatology” This article reviews the side effects of topical latanoprost therapy, particularly the hypertrichosis and pigmentation changes of eyelashes and nearby skin, and reports no new clinical results.
January 2015 in “Annals of dermatology/Annals of Dermatology” This report describes a case where travoprost treatment for open-angle glaucoma was associated with periocular hypertrichosis, hyperpigmentation, and eyelash growth, which gradually improved after discontinuation.
162 citations
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August 2002 in “Survey of Ophthalmology” This study found that latanoprost induces significant growth and pigmentation of lashes and ancillary hairs, with effects mirroring both brief and chronic treatments observed in patients and animal models.