96 citations,
March 2007 in “Developmental biology” The study found that the protein Dkk4 helps regulate hair growth by controlling Wnt signaling in mice.
75 citations,
August 2018 in “Plant physiology” Hydrogen sulfide disrupts protein function and root hair growth in plants by modifying proteins.
75 citations,
September 2016 in “EMBO journal” PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
67 citations,
May 2014 in “International Journal of Molecular Sciences” Using your own skin cells can help repair aging skin and promote hair growth.
61 citations,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
38 citations,
July 2020 in “EMBO journal” SIRT7 protein is crucial for starting hair growth in mice.
37 citations,
December 2021 in “Cells” Alopecia areata severity and treatment response are linked to specific cytokine levels.
35 citations,
January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
33 citations,
July 2007 in “Journal of cell science” Miz1 is essential for proper hair structure and growth.
32 citations,
July 2017 in “Molecular diagnosis & therapy” MicroRNA-21 could help diagnose and treat skin fibrosis.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
26 citations,
July 2021 in “Frontiers in Cell and Developmental Biology” The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.
24 citations,
March 2020 in “Cells” Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
24 citations,
December 2018 in “Inflammation and Regeneration” Phospholipase A2 enzymes play key roles in skin health and disease.
22 citations,
November 2016 in “International journal of molecular sciences” Vitamin D receptor is important for regulating hair growth and wound healing in mice.
22 citations,
December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
16 citations,
November 2021 in “Antioxidants” Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
15 citations,
October 2021 in “Frontiers in Pharmacology” Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.
15 citations,
July 2021 in “Bosnian Journal of Basic Medical Sciences” Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
15 citations,
April 2008 in “Headache” People with migraines often have mental health conditions, and treatment should be personalized to address both issues safely.
14 citations,
January 2020 in “Frontiers in Endocrinology” OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.
14 citations,
January 2019 in “PubMed” Vitamin D might be involved in the development of alopecia areata and could help in its treatment.
13 citations,
January 2023 in “Frontiers in Nutrition” Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.
11 citations,
October 2021 in “Stem Cell Research & Therapy” Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
11 citations,
July 2015 in “Journal of Anatomy” SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.
11 citations,
May 2012 in “Genesis” Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
10 citations,
August 2022 in “International Journal of Molecular Sciences” Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
10 citations,
June 2016 in “PLOS ONE” 9 citations,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
9 citations,
December 2022 in “Phytomedicine” More high-quality research is needed to recommend flavonoids and saponins for clinical use.