Hydrogen Sulfide Disturbs Actin Polymerization via S-Sulfhydration Resulting in Stunted Root Hair Growth

    August 2018 in “ Plant physiology ”
    Jisheng Li, Sisi Chen, Xiaofeng Wang, Cong Shi, Huaxin Liu, Jun Yang, Wei Shi, Junkang Guo, Honglei Jia
    TLDR Hydrogen sulfide disrupts protein function and root hair growth in plants by modifying proteins.
    The study concluded that hydrogen sulfide (H₂S) disrupted actin polymerization through S-sulfhydration, leading to stunted root hair growth in Arabidopsis thaliana. This disruption was linked to the modification of actin proteins, particularly ACTIN2 (ACT2) at Cys-287, which is crucial for actin filament stability. Elevated H₂S levels increased the G-actin/F-actin ratio, indicating reduced actin polymerization without degrading total actin. The findings underscored the significant impact of H₂S on root hair development and provided insights into the molecular mechanisms regulating actin dynamics and root morphology in plants.
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