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Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Cytokines are important for immune responses and treating diseases, but they can cause side effects like fever and skin issues.

High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Dutasteride injections can help hair growth in androgenic alopecia but need more research for long-term use.

Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.

New treatments and diagnostic methods for various animal skin conditions showed promising results.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Removing both ovaries treated the woman's excess male hormone symptoms.

Beta-HPV and MCPyV are linked to certain skin cancers, with ongoing research and vaccine development.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

High doses of fluconazole can cause reversible hair loss.

AI is effective in diagnosing and treating hair disorders, including detecting hair loss and scalp conditions with high accuracy, but it should supplement, not replace, doctor-patient interactions.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

New therapies are being developed that target integrin pathways to treat various diseases.

Keloid skin disorder involves abnormal fibroblast activation and immune response, linked to a group of genes including FGF11.

Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The document concludes that patients with skin of color need specialized dermatological care and education to manage unique skin conditions effectively.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Male pattern baldness is linked to a higher risk of certain skin cancers, especially on the scalp.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.