TLDR Alopecia mucinosa can be treated successfully with minocycline.
Alopecia mucinosa, marked by mucin buildup in hair follicles, was linked to benign and malignant conditions and was more common in adults. It appeared in three forms: primary idiopathic, malignancy-associated, and secondary to inflammation. Treatment was difficult, but a reported idiopathic case achieved full remission with minocycline. The review covered the condition's causes, histology, prevalence, treatment options, and outcomes.
76 citations
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October 2000 in “Journal of the American Academy of Dermatology” Follicular mucinosis can be an early sign of aggressive mycosis fungoides.
5 citations
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September 1989 in “Pediatric dermatology” Persistent papular plaques on children's faces need better understanding and treatment.
17 citations
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May 1987 in “Clinical and Experimental Dermatology” A patient with Sézary syndrome showed improvement after treatment and the study suggested follicular mucinosis might indicate future lymphoma risk.
51 citations
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May 1984 in “Journal of the American Academy of Dermatology” Benign follicular mucinosis involves immune cells attacking hair follicles.
20 citations
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April 1959 in “A M A Archives of Dermatology” Alopecia mucinosa causes red, raised skin patches and hair loss.
13 citations
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June 2020 in “International Journal of Dermatology” A rare scalp condition mainly in older women can be treated with various alternatives to steroids, which may have fewer side effects.
