Rapidly Progressing Mycosis Fungoides Presenting as Follicular Mucinosis

A patient with an aggressive folliculotropic variant of mycosis fungoides initially presented with follicular mucinosis and alopecia. Within 1 month, mycosis fungoides was confirmed, and the disease progressed to involve the inguinal lymph nodes within 3 months. A skin biopsy revealed prominent follicular mucinosis, folliculotropism of atypical cells, and intrafollicular Pautrier's microabscesses. The review suggested that follicular mucinosis could be an early indicator of rapidly progressing mycosis fungoides, with the folliculotropic variant having a more aggressive course than the classic form.