April 2024 in “AAPS PharmSciTech” New microneedle method improves hair regrowth treatment delivery.
January 2025 in “Journal of Materials Chemistry B” This abstract discusses androgenetic alopecia treatments like oral finasteride and topical minoxidil, reporting limited treatment efficacy and no new findings, and emphasizes the psychological impact on patients.
February 2025 in “Advanced Composites and Hybrid Materials” This study reported that in animal studies of androgenetic alopecia, a biodegradable microneedle patch releasing glutamic acid promoted hair regeneration more effectively than daily minoxidil, with higher hair follicle counts and less frequent dosing, showing the potential for clinical application.
November 2023 in “Advanced functional materials” This study suggests that inorganic magnesium silicate sprays can improve burn wound repair and promote regeneration of skin appendages, showing superior results compared to commercial wound healing products in animal models.
12 citations
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August 2017 in “Archives of Pharmacal Research” In this study, lecithin-based microparticle formulations of minoxidil showed enhanced skin penetration and comparable hair growth effectiveness to commercial products in mice, while minimizing skin irritation often seen with standard minoxidil solutions.
January 2025 in “Journal of Materials Chemistry B” A new treatment using special microneedles and a nitric oxide-releasing drug could improve hair growth and be more convenient for people with hair loss.
1 citations
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January 2022 in “Dermatologic therapy” This article discusses topical minoxidil-induced paresthesia and reports no new clinical findings.
1 citations
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January 2020 in “International Journal of Agriculture and Biology” In this study, researchers identified known and novel miRNAs in Liaoning Cashmere goat skin and found differences in miRNA expression linked to cashmere fineness, providing new insights into LCG goat skin biology.
1 citations
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January 2025 in “Regenerative Biomaterials” In this study, researchers found that exosomes derived from Pinctada martensii mucus can effectively inhibit melanin production in melanoma cells and zebrafish without adverse effects, potentially offering a promising therapeutic strategy for treating pigmentary disorders by modulating the NF-κB signaling pathway.
July 2026 in “Skin Appendage Disorders” This study observed that plant-derived extracellular vesicles delivered through a microneedling technique showed favorable tolerance and subjective improvement in androgenetic alopecia patients, with 95% reporting perceived improvement and 85% experiencing no adverse effects after six sessions.
January 2018 in “대한본초학회지(본초분과학회지)” This study found that SHJ extract increased hair growth and melanogenesis in mice, suggesting potential use in cosmeceuticals for hair care.
January 2013 in “프로그램북(구 초록집)” This study found that using a 0.5mm roller for microneedle therapy increased hair growth in mice and significantly affected the expression of hair growth-related molecules like VEGF.
14 citations
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January 2014 in “International Journal of Dermatology” Minoxidil with Korean red ginseng improves hair density and thickness more than minoxidil alone.
January 2021 in “Journal of clinical & experimental dermatology research” This study found that a new propylene glycol-free 5% minoxidil lotion demonstrated good clinical efficacy and very good cosmetic acceptability and tolerability after six months of use in patients with androgenetic alopecia, showing results comparable to traditional formulations containing propylene glycol.
1 citations
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July 2023 in “Cytotherapy” In this study, MSC-derived magnetic nanovesicles combined with a magnetic field increased skin retention and accelerated hair follicle growth in a mouse model of hair regeneration.
5 citations
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April 2023 in “Bioengineering & Translational Medicine” This study found that STAR particles, when applied to human skin, were well tolerated and highly acceptable at various pressures and with repeated daily use, suggesting they may provide a safe and effective method for enhancing drug delivery through the skin.
12 citations
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June 2011 in “Han-guk sikpum gwahakoeji/Han'gug sigpum gwahag hoeji/Han-guk sikpum gwahak hoeji” This study found that MBN, an herbal extract fermented by Lactobacillus plantarum, promoted hair growth and increased related gene expression in C57BL/6 mice.
July 2026 in “Vestnik dermatologii i venerologii” This study found that a serum with a minoxidil derivative and high-concentration niacinamide was effective in improving androgenetic alopecia in women, with 65.8% showing clinical recovery after 4 months, and reported good tolerability and increased treatment compliance.
June 2025 in “ACS Biomaterials Science & Engineering” In this study, researchers developed a new microneedle patch delivery system for minoxidil, which enhanced its controlled release and improved hair growth in mice, potentially offering better treatment outcomes for androgenetic alopecia.
1 citations
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May 2017 in “Journal of cosmetic and laser therapy” This study found that lasers and light devices may alleviate recalcitrant skin side effects in cancer patients treated with EGFR inhibitors, offering an alternative for those who do not respond to traditional therapies.
12 citations
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February 2022 in “Acta Biomaterialia” In this study, researchers found that dissolving microneedles made with hyaluronic acid enhanced the effectiveness of minoxidil in reducing hair loss and promoting hair growth in alopecia-affected mice more effectively than topical minoxidil alone, while using only 10% of the drug amount.
November 2022 in “Clinical, Cosmetic and Investigational Dermatology” In this study, a combined treatment for moderate to severe androgenetic alopecia using electric microneedles showed a 100% response rate after 12 weeks, with improvements in hair density and mild side effects, offering promising application prospects.
This research investigated the role of EphA1 in embryonic and adult tissues, generating mouse models suggesting potential links to skin and colon cancer, sepsis, and post-traumatic injury.
25 citations
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June 2015 in “Clinical, Cosmetic and Investigational Dermatology” This study found that using an electrical microneedling device enhanced the penetration of liposomal melanin-fluorescein into hair structures and widened the follicular infundibulum in ex vivo human skin models.
February 2026 in “International Journal of Cosmetic Science” This study found that a novel Mito-Activator Complex, containing nicotinamide and epigallocatechin gallate, significantly increased hair density and growth in a 6-month human trial, with no adverse effects reported, potentially offering a new approach to hair loss treatment through mitochondrial activation.
13 citations
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December 2021 in “Toxics” In this study, PEGDE above 10,000 μg/mouse caused subcutaneous toxicity including ulceration in mice, but did not affect liver, spleen, or kidney tissues.
January 2024 in “International Journal of Trichology” This study found that combining microneedling with a topical glycosaminoglycan lotion improved hair density and follicular thickness in patients with androgenetic alopecia, with no adverse effects except mild pain, suggesting potential synergistic benefits as a treatment.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that adipose stem cell exosomes, combined with microneedling, improved facial skin wrinkles, elasticity, hydration, and pigmentation compared to a placebo, with significant results on the Global Aesthetic Improvement Scale and no serious adverse events noted in treated individuals.
January 2026 in “Dermatologic Therapy” This study found that in patients with female androgenetic alopecia, mesodermal injection of 0.5% minoxidil was more effective in increasing hair density and improving hairline height than topical 2% minoxidil, with comparable safety over 16 weeks.
January 2025 in “Regenerative Biomaterials” In this study, a cerium-polypeptide hydrogel was found to effectively treat MRSA-infected wounds by promoting faster wound repair and reducing inflammation compared to a standard hydrogel.