FCP 8: Effect on Hair Growth Using Microneedle Devices in Hairless Mice

January 2013 in “ 프로그램북(구 초록집) ”

Eun Jung Ko, In Young Oh, Beom Joon Kim, Myeung Nam Kim

microneedle devices hair growth C57BL/6 mice needle length rolling cycles VEGF Wnt3a Wnt10b β-catenin microneedling microwounds tissue angiogenesis vascular endothelial growth factor Wnt signaling pathway

From the encyclopedia

Vascular Endothelial Growth Factor →

Microneedling →

technique to create small wounds in skin to activate collagen production and hair growth

Studysummary This study found that using a 0.5mm roller for microneedle therapy increased hair growth in mice and significantly affected the expression of hair growth-related molecules like VEGF.

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The study investigated the effects of microneedle devices on hair growth in C57BL/6 mice, focusing on the optimal needle length and rolling cycles. It was found that a 0.5 mm microneedle roller was most effective in promoting hair growth. The microneedling process influenced the regulation of hair growth-related factors, including VEGF, Wnt3a, Wnt10b, and β-catenin, with a significant increase in VEGF expression. The results suggested that microneedle-induced microwounds could positively impact hair growth and tissue angiogenesis.

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