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90-120 / 1000+ resultsresearch Recombinant Filaggrin-2 microneedles reverse androgenetic alopecia by rescuing mitochondrial dysfunction in dermal papilla cells
Recombinant Filaggrin-2 microneedles effectively promote hair growth and repair in hair loss.
research Upcycling waste hair and feathers derived keratin into intact cortical cell-derived micro-units via periodate oxidation: Applications & life cycle assessment
In this study, researchers developed a novel periodate oxidation method for extracting keratin micro-units from waste hair and feathers, achieving yields of 31.28% and 20.64% respectively, enhancing the stability of oil-in-water emulsions and suggesting potential for sustainable biomaterial production.
research Bletilla striata polysaccharide (BSP) promotes hair growth and suppresses oxidative stress and senescence of dermal papilla cells by inhibiting prostaglandin-endoperoxide synthase 2 (PTGS2)
research Multifunctional hydrogel based on oxidized sodium alginate and carboxymethyl chitosan delivers minoxidil loaded liposomes for the treatment of androgenetic alopecia
The hydrogel improves hair growth treatment by enhancing drug delivery and promoting follicle repair.
research Comprehensive characterization of keratin extracted from patients with androgenetic alopecia and healthy individuals through multimolecular spectroscopy and structural analysis
This study used a new multimolecular spectral method to uncover structural differences in hair keratin from individuals with androgenetic alopecia compared to healthy individuals, identifying potential biomarkers and providing insights for developing new treatments.
research Interaction of polypeptides with hair in different reducing environments
This study found that different polypeptides, including KP peptide and hydrolyzed keratin, can improve the mechanical properties of damaged hair under varying conditions, with reduction environments and cysteine content influencing their effectiveness.
research Enzymatic synthesis of biosafe hematoxylin dyes on hair: enhanced post-dyeing hair health and boosting color fastness
This study introduced an eco-friendly enzymatic hair dyeing process utilizing laccase-catalyzed polymerization of hematoxylin, achieving intense, long-lasting color comparable to commercial dyes while enhancing hair strength and offering antioxidant and UV-shielding benefits.
research Eco-engineered recombinant collagen III-PEG hydrogels with curcumin synergy for accelerated skin regeneration: A green crosslinking strategy in wound therapeutics
In an animal study with a skin defect model, this research reported that curcumin-loaded hydrogels made from recombinant humanized collagen and an eco-friendly crosslinker enhanced wound repair by promoting angiogenesis, granulation tissue formation, and hair follicle neogenesis, while providing antioxidant benefits.
research Smart bacteriophage release from bovine β-lactoglobulin fibrils based hydrogel with anti-MRSA, biofilm degradation and hair follicle regeneration functions for infected burn wound
A new hydrogel can kill resistant bacteria and help heal infected burn wounds.
research Fucoidan treatment reverses hair loss and inhibits inflammatory responses in a mouse model of androgenetic alopecia
Fucoidan may help regrow hair and reduce inflammation in hair loss.
research Bifunctional sodium hyaluronate microneedle patches integrating 5α-reductase and ROS regulation for boosted hair regeneration
This study developed a bifunctional sodium hyaluronate microneedle patch incorporating glycyrrhizin-loaded dutasteride micelles and mesoporous polydopamine nanoparticles, which effectively inhibited DHT and reduced ROS in hair follicle cells, resulting in significantly accelerated hair growth in vitro and in vivo.
research Positively charged chitosan-dissolving microneedles promote follicular accumulation of finasteride nanocrystals to treat androgenetic alopecia
A new microneedle system effectively delivers finasteride to treat hair loss.
research Borate-modified recombinant type XVII collagen microneedles loaded with IGF-1 for the treatment of androgenetic alopecia
In this study, an innovative microneedle platform loaded with IGF-1 and modified collagen was reported to significantly promote hair regeneration, enhance neovascularization, and reduce inflammation in a mouse model of androgenetic alopecia, outperforming the commonly used minoxidil treatment.
research Near-infrared light-triggered nitric oxide-releasing hyaluronic acid hydrogel for precision transdermal therapy of androgenic alopecia
This study developed a NIR light-triggered NO-releasing hydrogel that promotes angiogenesis, repairs damaged dermal papilla cells, reduces inflammation, and improves the nutrient supply and follicular environment in animal models, offering a promising treatment strategy for androgenic alopecia.
research Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis
This study found that decorin treatment significantly enhances dermal papilla cell proliferation, promoting hair follicle growth by influencing the SMAD3/TGF-β signaling pathway through exosomal miR-129–2-3p, which may aid in novel strategies for treating hair disorders and enhancing wool production.
research Extraction, purification, structural characterization, and bioactivities of Ginkgo biloba leave polysaccharides: A review
This review discusses recent advances in extracting, purifying, and analyzing polysaccharides from Ginkgo biloba leaves, which are valued in traditional Chinese medicine for their diverse biological activities, including antioxidant and hair-growth promoting effects, aiming to inform future development and commercialization.
research Cellulose nanocrystal-stabilized Pickering emulsion gels as vehicles for follicular delivery of minoxidil
This study reported that newly developed minoxidil Pickering emulsion gels, designed using cellulose stabilizers, showed promising results for promoting hair regrowth and targeting hair follicles by enhancing the delivery and stabilization properties of the formulation in a hair loss treatment context.
research All-in-one polysaccharide hydrogel with resistant vascular burst pressure and cooperative wound microenvironment regulation for fatal arterial hemorrhage and diabetic wound healing
This study reports that beta-glucan hybrid hydrogels, reinforced with laponite nanoclay, showed promising results in rat models for managing hemorrhage and diabetic wound healing by enhancing hemostasis, reducing inflammation, and promoting faster wound closure and tissue regeneration.
research Chitosan and its amphiphilic derivative nanoparticles loaded with Minoxidil for induction of hair growth: In vitro and in vivo evaluation
This study found that MCS nanoparticles improved Minoxidil's hair growth effects in an animal model compared to the commercial formulation, but they were less effective than CS nanoparticles despite showing better solubility with minimal side effects.
research Facile strategy for gelatin-based hydrogel with multifunctionalities to remodel wound microenvironment and accelerate healing of acute and diabetic wounds
This study demonstrates that an injectable gelatin-based hydrogel incorporating zirconium and quercetin promotes diabetic wound healing in vivo by enhancing angiogenesis, collagen deposition, and hair follicle regeneration while providing antibacterial and oxidative stress protection without detectable cytotoxicity.
research Development and characterization of polydeoxyribonucleotide (PDRN) loaded chitosan polyplex: In vitro and in vivo evaluation of wound healing activity
This study found that a chitosan/PDRN nanopolyplex significantly improved diabetic wound healing in rats by enhancing cell proliferation, migration, and antimicrobial activities, suggesting its potential as a therapeutic product.
research Platelet-rich plasma-loaded bioactive chitosan@sodium alginate@gelatin shell-core fibrous hydrogels with enhanced sustained release of growth factors for diabetic foot ulcer healing
This study reports that PRP-loaded bioactive fibrous hydrogels significantly enhance wound healing in diabetic foot ulcers by reducing inflammation and promoting tissue growth, with reduced administration frequency compared to standard PRP gel.
research Homo- and heteropolymer self-assembly of recombinant trichocytic keratins
This study presents recombinant human hair keratins K31 and K81, observing novel nanostructures from their self-assembly and emphasizing disulfide crosslinking's role in this process.
research Bioengineering Skin Constructs
This chapter reviews traditional and tissue-engineered treatments for skin defects and discusses advances in bioengineered skin constructs, but it presents no new experimental results.
research ELECTRON MICROSCOPE STUDIES OF HAIR AND WOOL
This article reports electron microscope studies on the structure of hair and wool, but it does not present new clinical findings.
research Cutaneous signs in COVID ‐19 patients: A review
This review discusses the cutaneous symptoms associated with COVID-19 and their potential use in diagnosing and assessing the severity of the disease, but it reports no new clinical results.
research Development of a Chitosan Nanofibrillar Scaffold for Skin Repair and Regeneration
This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.
research Biomaterials for in situ tissue regeneration: development and perspectives
This review discusses the development and future prospects of biomaterials for in situ tissue regeneration but reports no new research results; it underscores the importance of biomaterials in addressing tissue defects.
research Secreted subtilisin Sub3 from Microsporum canis is required for adherence to but not for invasion of the epidermis
This study found that the subtilisin protease Sub3 from Microsporum canis is essential for adherence to the feline epidermis but is not necessary for invading epidermal structures.