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Glossary Lymphocytic

cells related to immune system's white blood cells

Lymphocytic refers to anything related to lymphocytes, which are a type of white blood cell crucial for the immune system. These cells help the body fight off infections and are involved in immune responses. In medical contexts, "lymphocytic" is often used to describe conditions or reactions involving an increased number of lymphocytes, such as in certain types of inflammation or autoimmune diseases.

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research Treatment modalities for lymphocytic and neutrophilic scarring alopecia

August 2023 in “Journal of The American Academy of Dermatology”

This article discusses various treatments for primary cicatricial alopecia with a focus on early intervention to manage symptoms and improve hair density, but it reports no new clinical results.

research Topical gabapentin and its relation to cutaneous innervation in symptomatic lymphocytic primary cicatricial alopecia

April 2024 in “Skin health and disease”

In this pilot study, participants with lymphocytic primary cicatricial alopecia who applied 6% topical gabapentin solution twice daily for 12 weeks experienced significant symptom reduction, though there was no noticeable change in nerve fibre density or neuropeptide expression.

research An epidemiological study of 97 cases of primary cicatricial alopecia in Iran

12 citations , June 2015 in “Dermatology Reports”

This study found that discoid lupus erythematous was the most common type of primary cicatricial alopecia, predominantly affecting middle-aged women.

research Clinical features of primary cicatricial alopecia in Chinese patients

28 citations , January 2014 in “Indian Journal of Dermatology, Venereology and Leprology”

This study found that dermatoscopy is useful for diagnosing and assessing primary cicatricial alopecias in Chinese patients, with alopecia mucinosa having a distinct feature of patulous follicular openings.

research Primary cicatricial alopecias

1 citations , April 2010 in “Expert Review of Dermatology”

This review discusses primary cicatricial alopecias, detailing their classification, pathogenesis, clinical features, histopathologic findings, and treatment, without reporting new experimental results.

research Clinical features of 109 patients with primary cicatricial alopecia: a 15-year retrospective study

January 2026 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica”

In this study, cicatricial alopecias were classified by inflammatory cell type and the researchers highlighted that primary cicatricial alopecia's exact causes remain unknown, accounting for 6% of all hair diseases despite its unclear prevalence.

Scarring Alopecia: Overview and Treatment Options

research Scarring Alopecia

1 citations , June 2012 in “Actas Dermo-Sifiliográficas”

This article discusses primary cicatricial alopecia, highlighting the need for early and precise diagnosis to effectively manage and treat these complex inflammatory hair disorders, but presents no new clinical results.

research Primary Cicatricial Alopecias

18 citations , October 2012 in “Dermatologic Clinics”

This article discusses primary cicatricial alopecias, a group of rare inflammatory scalp disorders resulting in permanent hair loss, and reports no new findings.

research Unveiling a Shared Precursor Condition for Acne Keloidalis Nuchae and Primary Cicatricial Alopecias

1 citations , August 2023 in “Clinical, Cosmetic and Investigational Dermatology”

In this study, researchers observed that a hidden scalp condition could contribute to acne keloidalis nuchae and potentially other primary cicatricial alopecias, impacting their diagnosis and treatment.

Primary Cicatricial Alopecia: Treatment Approaches and Classification

research Primary cicatricial alopecia

95 citations , November 2016 in “Journal of The American Academy of Dermatology”

This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.

research Cicatricial Alopecias

May 2017 in “InTech eBooks”

This review discusses various types of primary cicatricial alopecias, categorized by the predominant type of inflammatory cells involved, and reports no new clinical results.

research Primary cicatricial alopecia

65 citations , November 2016 in “Journal of The American Academy of Dermatology”

This article reviews various types of primary cicatricial alopecias and emphasizes the importance of accurate diagnosis to improve management strategies, particularly detailing remaining lymphocytic forms and expanding on neutrophilic and mixed types.

research Developing human fetal skin demonstrates a unique lymphocyte signature

1 citations , June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

In this study, researchers identified unique prenatal lymphocyte features in human fetal skin, including proliferative naive T cells and memory-like T cells, which may influence antigen and allergen responses in utero and infancy.

Comparison of Alopecia Areata Induction in C3H/HeH Mice by Injection of Lymphocytes from Mice with Induced vs. Spontaneous Disease

research 066 Comparison of alopecia areata induction in C3H/HeH mice by injection of lymphocytes from mice with induced vs. spontaneous disease

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study investigates whether lymphocytes from mice with secondary alopecia areata can effectively induce the disease in a C3H/HeH mouse model, similar to lymphocytes from mice with spontaneous disease.

Cicatricial Alopecia: Overview and Treatment Recommendations

research Cicatricial alopecia

23 citations , April 2018 in “Journal der Deutschen Dermatologischen Gesellschaft”

This review discusses the classification and diagnosis of primary cicatricial alopecias and reports no new clinical results; it highlights the need for effective treatments owing to limited evidence of current therapies' efficacy.

research Immunopathogenesis of Primary Cicatricial Alopecia

December 2013 in “Research Portal (King's College London)”

This article discusses the anatomical and biological aspects of hair follicle stem cells in the bulge region but reports no new research findings.

Perifollicular Inflammation and Fibrosis in Androgenetic Alopecia: Implications for Diagnosis and Treatment - A Comparative Histopathologic and Clinical Study with Normal-Appearing Scalp

research Perifollicular Inflammation and Fibrosis in Androgenetic Alopecia: Implications for Diagnosis and Treatment - A Comparative Histopathologic and Clinical Study with Normal-Appearing Scalp

January 2026 in “Clinical Cosmetic and Investigational Dermatology”

This study found that targeting both hormonal and immune pathways improved treatment outcomes in androgenetic alopecia patients with an under-recognized inflammatory component called PIILIF, which may contribute to treatment resistance.

research What′s new in cicatricial alopecia?

16 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

This review explores new theories, diagnostic tools, and management strategies for primary cicatricial alopecia but reports no new clinical findings.

research Non-scarring patchy alopecia in patients with systemic lupus erythematosus differs from that of alopecia areata

30 citations , October 2013 in “Lupus”

This study identified distinct clinical and dermatoscopic features to differentiate non-scarring patchy alopecia in SLE from alopecia areata, emphasizing the value of serological tests in diagnosis.

Histopathological Findings of Uncomplicated Hair Transplant for Male Androgenetic Alopecia: Can Lichen Planopilaris Features Be Present?

research Histopathological Findings of Uncomplicated Hair Transplant for Male Androgenetic Alopecia: Can Lichen Planopilaris Features Be Present?

1 citations , January 2020 in “Skin appendage disorders”

This study questions whether lymphocytic infiltrate and fibrosis observed after uncomplicated hair transplants might be expected without indicating lichen planopilaris.

Cicatricial Alopecia: Overview and Treatment Options

research Cicatricial Alopecia

1 citations , October 2018 in “InTech eBooks”

This article reviews treatment approaches for cicatricial alopecia, describing how medication efficacy varies and suggesting autologous hair transplantation for stable cases; no new clinical data are presented.

research Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature

25 citations , November 2020 in “Cell Reports Medicine”

Developing human skin has immune cells with memory-like features.

research The Pathogenesis of Primary Cicatricial Alopecias

150 citations , October 2010 in “The American Journal of Pathology”

This review discusses the pathogenesis and challenges in treating primary cicatricial alopecia, highlighting the need to understand immune protection collapse in hair follicle stem cells; it reports no new clinical results.

research Primary cicatricial alopecia: Recent advances in understanding and management

44 citations , November 2011 in “The Journal of Dermatology”

This review discusses recent advancements in the management and diagnosis of primary cicatricial alopecias but reports no new clinical results; emerging insights suggest sebaceous gland dysfunction may play a role in their etiopathogenesis.

Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia

research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia

22 citations , June 2012 in “PLOS ONE”

In this study, researchers found that impaired cholesterol biosynthesis in hair follicles may trigger an inflammatory immune response linked to primary cicatricial alopecia, providing new insights into the disorder's pathogenesis.

Cicatricial Alopecia Research Foundation Meeting, May 2016: Progress Towards the Diagnosis, Treatment, and Cure of Primary Cicatricial Alopecias

research Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias

22 citations , January 2018 in “Experimental Dermatology”

This article reviews insights into the pathogenesis of primary cicatricial alopecias, such as lichen planopilaris, provided by emerging technologies, but it does not report new clinical results.

research Management of primary cicatricial alopecias: options for treatment

98 citations , May 2008 in “British Journal of Dermatology”

This review discusses evidence-based guidance for managing primary cicatricial alopecias but reports no new clinical results, highlighting significant gaps in knowledge and the need for more quality trials.

research Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of Alopecia

November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that disrupted cholesterol homeostasis impairs hair regrowth in individuals with primary cicatricial alopecia by damaging hair follicle stem cells, highlighting the importance of cholesterol in maintaining stem cell function and hair follicle integrity.

research The role of 3Rs in the age of One Health: where we are and where we’re going

October 2023 in “Biomedical science and engineering”

Innovative methods are reducing animal testing and improving biomedical research.

research Identification of drug-specific public TCR driving severe cutaneous adverse reactions

88 citations , August 2019 in “Nature communications”

In this study, researchers identified a specific T cell receptor associated with carbamazepine-induced severe cutaneous adverse reactions, demonstrating its potential for therapeutic development in patients with the HLA-B*15:02 genotype.