TLDR Middle-aged women in Iran are most affected by primary cicatricial alopecia, especially discoid lupus erythematous.
This study examined 97 cases of primary cicatricial alopecia (PCA) in Iran, finding a higher prevalence in middle-aged women (63.9%). Discoid lupus erythematous (DLE) was the most common histological type, also at 63.9%. There was no significant relationship between PCA types and variables such as job type, clinical findings, or sex. Lymphocytic PCA was more common in women, while neutrophilic PCA was more common in men. Common symptoms included itching, scalp tenderness, and ulceration. The study emphasized the need for further research to better understand PCA pathogenesis.
28 citations,
January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” Chinese patients with primary cicatricial alopecia often have folliculitis decalvans, benefit from treatment, but may experience relapse, with dermoscopy being a useful diagnostic tool.
16 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
16 citations,
January 2011 in “Indian Journal of Dermatology” Most patients with cicatricial alopecias face significant psychological and social challenges due to their hair loss.
150 citations,
November 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
254 citations,
January 2004 in “Journal of the American Academy of Dermatology” Accurate diagnosis and aggressive treatment are crucial to prevent permanent hair loss in cicatricial alopecia.
