110 citations
,
January 2014 in “Journal of Controlled Release” Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.
39 citations
,
July 2008 in “Dermatologic Therapy” This review provides a practical approach to diagnosing pseudopelade of Brocq and updates on treatment options but reports no new clinical results.
2 citations
,
December 2013 in “Journal of dermatology” This letter reports a homozygous missense mutation in the LIPH gene causing autosomal recessive hypotrichosis simplex in a Chinese patient.
13 citations
,
August 2020 in “Mayo Clinic proceedings” In this study, women with lichen planopilaris were found to have high rates of thyroid disease, depression, and anxiety, and about half experienced slowed or stabilized disease progression with treatment.
80 citations
,
April 2011 in “Plant physiology” This study suggests that the GPX-PDE1 and GPX-PDE2 genes in white lupin enhance root hair development and contribute to Pi limitation acclimation by facilitating glycerophosphodiester degradation.
September 2024 in “Journal of the American Academy of Dermatology” In this case report, a 53-year-old woman with Little-Graham-Piccardi-Lassueur-Syndrome responded well to a treatment regimen of hydroxychloroquine, methotrexate, and other therapies, effectively halting the progression of this rare dermatosis characterized by alopecia and hyperkeratotic eruptions.
April 2018 in “Journal of Investigative Dermatology” This study found that the PPAR-γ modulator AGED can reverse epithelial-mesenchymal transition in hair follicles affected by lichen planopilaris ex vivo, suggesting potential for treating scarring alopecias.
3 citations
,
May 2022 in “Clinical and experimental dermatology” This review discusses potential EMT-targeting drugs for treating lichen planopilaris and emphasizes the need for clinical trials, as current evidence is limited to individual cases or case series.
April 2024 in “JAAD Case Reports” This article summarizes the clinical presentation of lichen planopilaris and emphasizes its prevalence among women aged 25 to 70, but reports no new clinical results.
12 citations
,
June 2020 in “Journal of The American Academy of Dermatology” This article discusses platelet-rich plasma therapy for cicatricial alopecias like lichen planopilaris and reports no confirmed new clinical results; the authors highlight ongoing uncertainty about its effectiveness and potential risks.
35 citations
,
November 2019 in “Journal of the American Academy of Dermatology” This study reviewed 40 patients with scalp symptoms and identified a new variant of diffuse lichen planopilaris in 20 individuals, suggesting these conditions should be considered in similar cases.
3 citations
,
January 2005 in “Biological & Pharmaceutical Bulletin” This study reports that the peptide GPIGS, found in Bacillus sp. M18 conditioned medium, may promote hair growth through the PI-3K/Akt pathway and accelerate hair regrowth in mice.
2 citations
,
January 2024 in “Advances in Dermatology and Allergology” This study suggests a potential role for S100A7 and IL-17 in the pathogenesis of lichen planopilaris.
November 2020 in “Acta Medica Bulgarica/Acta medica Bulgarica” This case report details two patients with Graham-Little-Piccardi-Lassueur syndrome who showed marked skin lesion improvement with corticosteroid treatment, though cicatricial scalp alopecia remained unresponsive.
1 citations
,
September 2016 in “Dermatologic Surgery” New hair loss subtype found, mimics common baldness.
160 citations
,
December 2016 in “Journal of biophotonics” This review discusses the evolution and potential of photobiomodulation therapy, highlighting its transition from skepticism to recognition in medical research; it reports no new experimental findings.
21 citations
,
September 2018 in “International journal of women’s dermatology” In this study, patients with lichen planopilaris showed higher prevalence of autoimmune disorders like Hashimoto's thyroiditis and hypothyroidism compared to those with seborrheic dermatitis.
May 2025 in “International Medical Case Reports Journal” This case report highlights lichen planus pigmentosus in a 60-year-old man, which was linked to previously undetected hepatitis C infection and liver cirrhosis, suggesting a need for hepatitis C testing in patients with similar dermatological manifestations.
July 2026 in “Frontiers in Endocrinology” This study observed that beef cattle with certain prolactin receptor gene mutations, known as slick mutations, demonstrated improved post-weaning growth and temperature regulation in a hot, humid climate compared to other genotypes, suggesting genotype influences growth efficiency and heat tolerance.
9 citations
,
September 2018 in “JAAD Case Reports” This article describes a unique case of lichen planopilaris with a previously unreported trigger in one of the youngest documented adult patients, without providing new clinical results or data.
July 2025 in “Frontiers in Medicine” This study identified compound heterozygous mutations, c.1101del and c.736 T > A, in the LIPH gene responsible for causing autosomal recessive woolly hair in a child, with c.1101del being a novel frameshift mutation.
102 citations
,
July 2007 in “Genes & Development” This study found that maternal PPARγ is essential for preventing the production of inflammatory lipids in mouse milk, which can otherwise cause inflammation, alopecia, and growth retardation in nursing pups.
206 citations
,
September 2010 in “PLoS ONE” This study found that using a Picosecond IR Laser (PIRL) on mouse skin led to less tissue damage and scarring compared to conventional surgical lasers and tools.
January 2013 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” This study observed that hormone replacement therapy and autoimmune diseases may be more common among women with frontal fibrosing alopecia compared to those with androgenetic alopecia.
July 2018 in “Elsevier eBooks” This study highlights lichen planopilaris as a form of scarring hair loss with symptoms like shedding and itching, and notes successful treatment options such as topical and oral antiinflammatory medications to preserve hair follicles by early intervention.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” LIPH mutations cause woolly hair in some Chinese people.
October 2014 in “Journal of the Portuguese Society of Dermatology and Venereology” This paper presents a therapeutic approach with excellent results in a case of lichen planopilaris overlapping with dermatomyositis and scleroderma, although broader applicability is not discussed.
January 2005 in “Life sciences” This review discusses the pathophysiologic role of lysophosphatidic acid in the skin and reports no clinical results, suggesting pharmacological inhibition as a potential treatment for various skin disorders.
19 citations
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March 2011 in “The Journal of Dermatology” This case report in a child suggests that lichen planus pemphigoides may represent a heterogeneous group of disorders, potentially triggered by conditions like varicella.
January 2025 in “Cellular and Molecular Biology” This study found that in Liaoning cashmere goats, overexpression of the PIP5K1A gene enhances skin fibroblast proliferation, while interference with this gene reverses melatonin-induced proliferation, and PIP5K1A regulates certain miRNA expressions, suggesting a role in improving cashmere yield and quality.