April 2017 in “Australasian Journal of Dermatology” This study observed that systemic acitretin improved symptoms in 75% of lichen planopilaris patients, despite varied responses and a dominant female prevalence.
3 citations
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February 2019 in “Animal biotechnology” In this study, the PLP2 gene was found to promote secondary hair follicle development in Liaoning cashmere goats, with its expression negatively regulated by melatonin and potentially affecting follicle development via the BMP pathway.
January 2026 in “Clinical Case Reports” This review discusses the etiology of moth-eaten alopecia patterns in lichen planopilaris and emphasizes the importance of early diagnosis and treatment to prevent permanent scarring, offering no new empirical findings.
16 citations
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May 2000 in “Endocrinology” This study identified a new gene, mrp4, in mice, which suggests it may have a unique role in the growth and development of hair follicles in the ears and tails.
June 2017 in “Journal of The American Academy of Dermatology” Most men with lichen planopilaris had it confirmed by biopsy and often had thyroid issues, sexual dysfunction, or prostate cancer, hinting at a link with hormonal problems.
March 2024 in “Case Reports in Dermatology” This report details a case where diffuse lichen planopilaris and female pattern hair loss in a 32-year-old woman mimicked diffuse alopecia areata, highlighting the diagnostic value of dermoscopy-guided biopsies and the importance of timely treatment to prevent disease progression.
1 citations
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May 2016 in “Aktuelle Dermatologie” This case study reported that a 34-year-old woman with classic lichen planopilaris achieved disease remission after two months of hydroxychloroquine treatment following ineffective corticosteroid therapy.
5 citations
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August 2001 in “International Journal of Dermatology” This case study reports a 20-year-old laborer's progressive hair loss with scalp and body lesions, diagnosed as lichen planopilaris, leading to scarring alopecia resembling male-pattern baldness.
June 2023 in “British Journal of Dermatology” In this case series, researchers observed a rare presentation of lichen planopilaris confined to the face in six patients, with dermoscopic and histopathological profiles indicating scarring alopecia and pigment changes, and suggested that shaving and mustard oil use might trigger the condition.
This case study reports that a 35-year-old woman developed nonscarring alopecia following the cosmetic use of poly-L-lactic acid on her face and hairline.
June 2026 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This study concluded that oral tofacitinib significantly improved symptoms in patients with lichen planus pigmentosus who did not respond to conventional treatments, showing it as a viable alternative.
2 citations
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November 2023 in “Indian Dermatology Online Journal” In this case report, a 4-year-old Indian girl with linear and annular lupus panniculitis of the scalp achieved complete remission and hair regrowth with oral corticosteroids, showing no relapse after 6 months of follow-up.
April 2023 in “IP Indian journal of clinical and experimental dermatology” This article reviews the pathogenesis, complications, and management of lichen planus, especially its persistent oral form, and highlights the need for further prospective studies.
28 citations
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November 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the selective PPARγ modulator GMG-43AC may inhibit unwanted hair growth by inducing catagen phase while preserving hair follicle epithelial progenitor cells, suggesting potential in anti-hirsutism therapy.
5 citations
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September 2021 in “Clinical case reports” This case report documents the first known instance of Graham‐Little Piccardi Lassueur Syndrome in Saudi Arabia, observed in an adult dark-skinned male.
July 2022 in “Journal of Investigative Dermatology” This study suggests that using a non-medicated, hypo-allergenic scalp clarifying shampoo may improve hair volume and reduce shedding in women with lichen planopilaris and female pattern hair loss.
7 citations
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September 2024 in “BMC Genomics” In this study, whole-genome sequencing of Lanping black-boned sheep identified ERBB4 and ROR1 genes as potentially important in their distinctive hyperpigmentation, enhancing understanding of their genetic evolution from Lanping normal sheep.
December 2024 in “Biochemical and Biophysical Research Communications” LMWP-PDGFA shows promise for improving hair health and treating hair loss with fewer side effects.
September 2025 in “International Journal of Medical Informatics” A machine learning model can predict scarring in lichen planopilaris using factors like vitamin D levels and diagnostic delay.
4 citations
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September 2017 in “Dermatologic surgery” This article contains no new research findings or results.
66 citations
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January 2010 in “Journal of The American Academy of Dermatology” This study reported that mycophenolate mofetil was effective in reducing signs and symptoms of active lichen planopilaris in 83% of patients who had failed multiple prior treatments.
23 citations
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January 2010 in “Journal of The American Academy of Dermatology” This article discusses the efficacy and safety of mycophenolate mofetil and hydroxychloroquine for treating lichen planopilaris and reports no new clinical results.
1 citations
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December 2012 in “Dermatologic Surgery” Hair transplants can risk reactivating lichen planopilaris, a scarring hair loss condition.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that mitochondrial dysfunction might contribute to the pathogenesis of Lichen planopilaris by triggering a metabolic shift that leads to chronic inflammation and hair follicle damage.
39 citations
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March 2008 in “British Journal of Dermatology” This study documented the onset of lichen planopilaris during treatment with etanercept.
1 citations
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May 2024 in “International Journal of Innovative Science and Research Technology (IJISRT)” This review analyzed recent studies and concluded that JAK inhibitors are effective for treating lichen planopilaris, though concerns about long-term safety remain and further research is needed.
February 2024 in “Institutional Repository of the Federal Technological University of Paraná (RIUT) (Federal University of Technology – Paraná)” This review examines the molecular effects of photobiomodulation therapy, particularly its influence on gene and protein expression related to inflammation and cell functions, but reports no new clinical results.
January 2026 in “International Journal of Surgery Case Reports” This case series reports that home use of intense pulsed light devices may effectively reduce hair burden and prevent recurrence of pilonidal disease in patients unable to regularly attend clinic sessions.
155 citations
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June 2009 in “International Journal of Dermatology” This extensive review discusses the clinical manifestations, potential associations, and treatment approaches for lichen planus, but reports no new clinical results, highlighting gaps in evidence for therapeutic strategies.
26 citations
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December 2020 in “Photodermatology Photoimmunology & Photomedicine” This review discusses photobiomodulation as a potential treatment for hair loss, highlighting its safety and possible effectiveness but noting cost, protocol standardization, and expectation management as limitations; it reports no new clinical results.