Lichen Planopilaris: A Case Study of Progressive Hair Loss
August 2001
in “
International Journal of Dermatology
”
lichen planopilaris hair loss pruritis scalp follicular papules perifollicular erythema epidermal atrophy basal cell vacuolization keratin plugs dermal fibrosis lympho-histiocytic infiltrate sebaceous glands arrectores pilorum sweat glands itching skin inflammation hair follicle blockage skin thinning immune cell infiltration
Studysummary This case study reports a 20-year-old laborer's progressive hair loss with scalp and body lesions, diagnosed as lichen planopilaris, leading to scarring alopecia resembling male-pattern baldness.
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The document described a case study of a 20-year-old laborer who began experiencing symptoms of lichen planopilaris (LPP) at age 10, characterized by progressive hair loss on the scalp, pruritis, and slate-blue eruptions. The condition led to complete hair loss on the scalp, resembling male-pattern baldness, with grayish-blue follicular papules and perifollicular erythema. Histological examination of the scalp lesions showed uniform epidermal atrophy, basal cell vacuolization, and dilated hair follicles filled with keratin plugs, alongside dermal fibrosis and lympho-histiocytic infiltrate. The study highlighted the absence of hair follicles and sebaceous glands, while arrectores pilorum and sweat glands were preserved.