Search
for

    GlossarySkin Fibrosis (Dermal Fibrosis)

    excessive fibrous tissue buildup in skin causing thickening

    Skin fibrosis, also known as dermal fibrosis, is a condition characterized by the excessive accumulation of fibrous connective tissue in the skin. This can result from chronic inflammation, injury, or diseases such as scleroderma. The overproduction of collagen leads to thickening, hardening, and scarring of the skin, which can impair its normal function and elasticity.

    Related Terms

    Learn

    5 / 11 results

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn Redensyl

      commercial product with a blend of mostly natural ingredients for hair regrowth

    Research

    5 / 1000+ results

    Community Join

    5 / 1000+ results

      community I think I’ve finally found the reason for my hair loss

      in Chat  98 upvotes 2 weeks ago
      The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.

      community The Big Fat Layer II

      in Research/Science  26 upvotes 3 years ago
      Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  743 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community The Big Fat Layer / Remedies: Cetirizine

      in Treatment  12 upvotes 3 years ago
      Treating hair loss with various remedies, such as Cetirizine and the Big3 complex (minoxidil, finasteride, and RU58841), which have properties like adipogenic, anti-fibrotic and anti-inflammatory. References to research studies are also included.