Lichen Planus Pigmentosus as a Cutaneous Extrahepatic Manifestation of Chronic Hepatitis C Virus Infection: A Case Report

    May 2025 in “ International Medical Case Reports Journal ”
    Erda Avriyanti, Nur Mala Il, Endang Sutedja, Laila Tsaqilah, Chaerani Pratiwi Firdaus, Eva Krishna Sutedja, Hermin Aminah Usman, Risa Hidayah
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    TLDR Lichen planus pigmentosus may indicate undetected hepatitis C infection.
    This case report presents lichen planus pigmentosus (LPP) as a potential cutaneous extrahepatic manifestation of chronic hepatitis C virus (HCV) infection in a 60-year-old male with itchy, dark brown macules on his face. The diagnosis of LPP, alongside chronic HCV infection and liver cirrhosis, underscores the importance of testing for HCV in patients with LPP or similar skin conditions, as these may indicate undetected HCV infections. Treatment involving sun avoidance, photoprotection, topical steroids, and direct-acting antiviral agents resulted in clinical improvement, highlighting the need for awareness of HCV's diverse manifestations beyond liver-related symptoms.
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