A Prospective Case Control Study on Metabolic Syndrome in Lichen Planus in a Tertiary Care Centre

    August 2017 in “ International Journal of Research in Dermatology ”
    Girlly Kurian, Sundar Krishnan, P. Shakthi
    Image of study
    TLDR Lichen planus is not linked to metabolic syndrome, but it is associated with higher rates of high blood pressure, high triglycerides, and low HDL cholesterol.
    In a hospital-based case control study conducted from January 2015 to May 2016, researchers examined the potential association between metabolic syndrome and lichen planus, an autoimmune, inflammatory disease affecting the skin and mucous membrane. The study involved 40 cases of lichen planus and 80 age and sex matched controls. The results showed no significant association between metabolic syndrome and lichen planus (p=0.292). However, there was a higher prevalence of hypertension (47.5% vs. 27.5%, p=0.029), elevated triglyceride levels (25% vs. 10%, p=0.030), and low HDLC levels (65% vs. 45%, p=0.039) in patients with lichen planus. No significant association was found between fasting blood sugar and waist circumference with lichen planus. The study concluded that while metabolic syndrome was not significantly associated with lichen planus, its components such as hypertension, elevated triglycerides, and low HDLC levels were significantly associated with the disease. Therefore, patients with lichen planus should be screened for these parameters to prevent potential complications.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 37 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I've tried everything and my hair is still thinning

      in Chat  6 upvotes 9 months ago
      The user has tried finasteride, oral minoxidil, iron supplements, vitamin D, and vitamin B12, but their hair is still thinning after 5 years. Another user suggested trying dutasteride.

      community Clascoterone (Winlevi) Update for Canada

      in Treatment  16 upvotes 2 years ago
      Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 2 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

    Similar Research

    5 / 1000+ results