Evaluation of Cardiovascular Disease Risk Factors in Patients with Mycosis Fungoides

February 2015 in “ Anais Brasileiros de Dermatologia ”

Fatma Pelin Cengiz, Nazan Emiroğlu

mycosis fungoides high-sensitivity C-reactive protein homocysteine low-density lipoprotein cholesterol total cholesterol cytokines TNF-α IL-6 HSCRP LDLc

TLDR Patients with mycosis fungoides have a higher risk of heart disease.

Between January 2011 and November 2011, a study involving 32 patients with mycosis fungoides (MF) and 26 healthy controls found that the MF patients had significantly higher levels of high-sensitivity C-reactive protein (HSCRP), homocysteine, low-density lipoprotein cholesterol (LDLc), and total cholesterol. There were positive correlations between homocysteine and total cholesterol, as well as HSCRP and LDLc in the MF group. The study concluded that MF patients have an increased cardiovascular risk and stressed the need for dermatologists to investigate metabolic derangements in these patients. The document also notes that cytokines like TNF-α and IL-6, which are elevated in MF lesional skin, are associated with the pathogenesis of both MF and cardiovascular diseases, suggesting a shared inflammatory pathway.

View this study on scielo.br →

Discuss this study in the Community →

Research cited in this study

1 / 1 results

research Androgenetic Alopecia in Men Aged 40-69 Years: Prevalence and Risk Factors

155 citations, December 2003 in “British Journal of Dermatology”

Hair loss increases with age; alcohol raises risk, more female partners lowers it.

Similar Research

5 / 694 results

Development of a Non-Parametric Population Pharmacokinetics Model and Bayesian Estimator for Tacrolimus in Tunisian Renal Transplant Patients

research Development of a Non-Parametric Population Pharmacokinetics Model and Bayesian Estimator for Tacrolimus in Tunisian Renal Transplant Patients

March 2017 in “Fundamental & Clinical Pharmacology”

The model and estimator can predict drug exposure in kidney transplant patients well.

research Vitamin D in Dermatology and Cosmetology

June 2022

Vitamin D is crucial for skin health and managing skin diseases.

research Clinical and Biological Impact of the Exposome on the Skin

77 citations, July 2020 in “Journal of the European Academy of Dermatology and Venereology”

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

research Dermatologic Conditions of the Early Post-Transplant Period in Hematopoietic Stem Cell Transplant Recipients

5 citations, October 2018 in “American Journal of Clinical Dermatology”

Skin problems are common after stem cell transplants, and early treatment by dermatologists can improve patient outcomes.

research Abstracts from the 2009 Annual Meeting of the Society for Pediatric Dermatology

September 2009 in “Pediatric Dermatology”

UVB is good for a skin condition in Asian kids, a lotion works for head lice, a drug helps with a skin blistering disorder, a foam reduces itchiness in skin inflammation, birthmarks can be more widespread, and criteria for a neurocutaneous disorder were agreed upon.