Folliculotropic CD8+ Mycosis Fungoides Associated with Diffuse Mucosal Involvement
September 2018
in “
JAAD case reports
”
TLDR A rare type of skin cancer with mucosal involvement was partially treated but eventually relapsed.
The document reported a case of a 53-year-old woman with folliculotropic and syringotropic CD8+ mycosis fungoides (MF) that involved diffuse mucosal areas, including the oral, esophageal, and vulvar regions, leading to significant symptoms and weight loss. Despite antifungal and corticosteroid treatments being ineffective, subcutaneous methotrexate provided partial remission before relapse, after which liposomal doxorubicin was administered. The patient survived 4 years post-symptom onset without progression to cutaneous, lymph node, or visceral involvement. This case highlighted the rarity and complexity of CD8+ MF with mucosal involvement, which is often underreported and associated with advanced disease stages.
