TLDR A rare type of skin cancer with mucosal involvement was partially treated but eventually relapsed.
The document reported a case of a 53-year-old woman with folliculotropic and syringotropic CD8+ mycosis fungoides (MF) that involved diffuse mucosal areas, including the oral, esophageal, and vulvar regions, leading to significant symptoms and weight loss. Despite antifungal and corticosteroid treatments being ineffective, subcutaneous methotrexate provided partial remission before relapse, after which liposomal doxorubicin was administered. The patient survived 4 years post-symptom onset without progression to cutaneous, lymph node, or visceral involvement. This case highlighted the rarity and complexity of CD8+ MF with mucosal involvement, which is often underreported and associated with advanced disease stages.
8 citations,
August 2016 in “Journal of Cutaneous Pathology” Scalp biopsies are crucial for diagnosing hair loss causes in cutaneous lymphoma patients.
August 2021 in “Acta Haematologica Polonica” Folliculotropic mycosis fungoides has a worse prognosis than other types, with survival rates varying significantly based on subtype and organ involvement.
14 citations,
January 2014 in “Annals of Dermatology” Some cases of folliculotropic mycosis fungoides may progress slowly and not need aggressive treatment.
July 2011 in “British Journal of Dermatology” Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.
37 citations,
September 2008 in “The American journal of surgical pathology” Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."
8 citations,
August 2016 in “Journal of Cutaneous Pathology” Scalp biopsies are crucial for diagnosing hair loss causes in cutaneous lymphoma patients.
