Two Clinically Unusual Cases of Folliculotropic Mycosis Fungoides: One with and the Other without Syringotropism
January 2014
in “
Annals of Dermatology
”
folliculotropic mycosis fungoides cutaneous T-cell lymphoma syringotropism cystic lesions comedo-like lesions acneiform lesions generalized body hair loss pruritus hidradenitis suppurativa-like lesions hypohidrosis lichen planopilaris-like features hair loss itching sweat gland involvement acne-like lesions hidradenitis suppurativa
TLDR Some cases of folliculotropic mycosis fungoides may progress slowly and not need aggressive treatment.
The document discussed two cases of folliculotropic mycosis fungoides, a rare form of cutaneous T-cell lymphoma, with one case also exhibiting syringotropism. Both cases showed cystic, comedo-like, acneiform lesions, generalized body hair loss, pruritus, and hidradenitis suppurativa-like lesions. Unique to the first case were hypohidrosis and nail and palmoplantar involvement with lichen planopilaris-like features. Despite the typically aggressive nature of follicular mycosis fungoides, these cases had a slowly progressive but persistent course. The study emphasized the need for multiple, deep biopsy specimens for diagnosis and suggested that aggressive treatment might not be necessary for indolent cases, particularly those with syringotropism.
