Two Clinically Unusual Cases of Folliculotropic Mycosis Fungoides: One with and the Other without Syringotropism
January 2014
in “
Annals of Dermatology
”
folliculotropic mycosis fungoides cutaneous T-cell lymphoma syringotropism cystic lesions comedo-like lesions acneiform lesions generalized body hair loss pruritus hidradenitis suppurativa-like lesions hypohidrosis lichen planopilaris-like features hair loss itching sweat gland involvement acne-like lesions hidradenitis suppurativa
Studysummary This report describes two cases of folliculotropic mycosis fungoides with syringotropism, highlighting indolent progression despite the disease's typically aggressive nature, suggesting aggressive treatment might not be necessary. Our plain-language summary of this paper — not a Tressless recommendation.
The document described two clinically unusual cases of folliculotropic mycosis fungoides (FMF), a rare variant of cutaneous T-cell lymphoma, with one case involving syringotropism. Both cases presented with severe itching, loss of body hair, and acneiform lesions, and had a slowly progressive clinical course. Case 1, a 50-year-old man, showed significant improvement with acitretin and PUVA therapy, while Case 2, a 57-year-old man, responded modestly to the same treatment. The study highlighted the diagnostic challenges of FMF and the importance of recognizing atypical presentations to guide appropriate treatment strategies and improve patient outcomes.
