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      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Azelaic Acid

      acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community What are these spots on my scalp

      in Treatment  51 upvotes 4 months ago
      A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

      community I shaved my head. Trust the progress guys

      in Shaved/buzzed  456 upvotes 3 weeks ago
      The user shaved their head and is using finasteride and minoxidil for hair loss, expressing confidence in the process despite challenges. They are considering additional treatments like microneedling and are open to trying different looks, including facial hair growth.