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GlossaryDoxorubicin (Doxil)

chemotherapy drug that interferes with cancer cell DNA

Doxorubicin, also known as Adriamycin, is a chemotherapy drug used to treat various types of cancer, including breast cancer, bladder cancer, and lymphoma. It works by interfering with the DNA inside cancer cells, preventing them from growing and dividing. However, it can also cause side effects such as hair loss (alopecia) and damage to the heart, so its use is carefully monitored by healthcare professionals.

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Reduced Cardiotoxicity and Comparable Efficacy in a Phase III Trial of Pegylated Liposomal Doxorubicin HCl (CAELYX/Doxil) Versus Conventional Doxorubicin for First-Line Treatment of Metastatic Breast Cancer

research Reduced Cardiotoxicity and Comparable Efficacy in a Phase III Trial of Pegylated Liposomal Doxorubicin HCl (CAELYX/Doxil) Versus Conventional Doxorubicin for First-Line Treatment of Metastatic Breast Cancer

1461 citations , March 2004 in “Annals of oncology”

Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.

$Doxil (Caelyx): An Exploratory Study with Pharmacokinetics in Patients with Hormone-Refractory Prostate Cancer$

research Doxil (Caelyx): An Exploratory Study with Pharmacokinetics in Patients with Hormone-Refractory Prostate Cancer

81 citations , February 2000 in “Anti-cancer drugs”

Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.

research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy

522 citations , January 2001 in “Cancer investigation”

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

research Copper-Doxorubicin as a Nanoparticle Cargo Retains Efficacy with Minimal Toxicity

102 citations , October 2010 in “Molecular Pharmaceutics”

Copper-doxorubicin nanoparticles effectively treat tumors with less toxicity.

research Folliculotropic CD8+ Mycosis Fungoides Associated with Diffuse Mucosal Involvement

2 citations , September 2018 in “JAAD case reports”

A rare type of skin cancer with mucosal involvement was partially treated but eventually relapsed.

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community When I was in my 20s, skinny and with long hair, one of my biggest fear was being fat and bald in my 40s. Now that it’s come to pass, I’ve found there are better things to worry about. I started shaving my head in 05 when I was 32 and I can sum it all up in one word: Liberating.

in Shaved/buzzed 478 upvotes 4 years ago

Accepting hair loss, with solutions discussed including Minoxidil and Finasteride treatments, shaving the head as a liberating experience, and using beards to make up for lack of hair.

community 5 months on Minoxidil and 1 mg Fin every day.

in Update 483 upvotes 4 years ago

A user's experience with hair loss treatments such as minoxidil and finasteride, which has resulted in positive results. Others have also shared their experiences with similar treatments with encouraging results.

community Are Derma Rollers Actually Harmful in the Long Run?

in Microneedling 40 upvotes 6 months ago

Derma rollers may cause scarring alopecia, leading some to prefer dermastamps or dermapens for microneedling. Combining minoxidil with microneedling is effective, but proper technique and healing time are essential to prevent damage.

community Drinking topical Min is going too far…

in Minoxidil 433 upvotes 2 years ago

Various methods of using minoxidil, including taking it orally, to treat hair loss. Finasteride is also mentioned as another treatment option.

community Starting Pyrilutamide BID. First dose was yesterday. Diffuse thinning. I will put my full regimen below.

in Research/Science 88 upvotes 2 years ago

A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.

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