Patchy Hair Loss, Hyperpigmented Plaques, and Hyperkeratotic Papules in a Middle-Aged Woman
September 2024
in “
Journal of the American Academy of Dermatology
”
TLDR The patient responded well to treatment with no disease progression.
A 53-year-old woman with Little-Graham-Piccardi-Lassueur-Syndrome (LGPLS), a rare lichenoid dermatosis, presented with severe pruritus, progressive hair loss, and itchy erythematous plaques. Examination revealed scaly alopecic plaques, hyperpigmented plaques, and hyperkeratotic papules. Trichoscopy and dermoscopy confirmed irregular alopecic areas and follicular plugging. Histopathology diagnosed lichen planus and lichen planopilaris. Treatment included oral prednisone, topical clobetasol, hydroxychloroquine, methotrexate, folic acid, topical tacrolimus, and minoxidil. The patient showed an adequate response with no progression of the dermatosis.