Lichen Planopilaris – A Case Report Associated with Autoimmune Diseases

October 2014 in “ Journal of the Portuguese Society of Dermatology and Venereology ”

Luana Oliveira Ramos, Ana Paula Klein, Ana Paula Gualda Botelho Dos Santos, Fábio Francesconi

líquen plano pilar alopecia autoimmune condition fibrosis hair follicle dermatomyositis scleroderma

TLDR Early recognition and treatment of LPP can prevent hair loss and improve quality of life.

Líquen plano pilar (LPP) é uma condição autoimune que causa alopecia permanente e pode levar a distúrbios psicossociais e menor qualidade de vida. Embora LPP possa coexistir com doenças imunológicas sistêmicas, essa relação não era bem compreendida. O reconhecimento precoce e a terapia imediata eram essenciais para proteger os folículos pilosos de fibrose e impedir a progressão da perda de cabelo. O documento relatou um caso de LPP associado a dermatomiosite e esclerodermia, onde uma terapêutica específica mostrou excelentes resultados.

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Research cited in this study

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research Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: A Systematic Review

117 citations , March 2013 in “Journal of the European Academy of Dermatology and Venereology”

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

research Autoimmune Disease and Hair Loss

35 citations , October 2012 in “Dermatologic Clinics”

Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.

research Lichen Planopilaris: Update on Diagnosis and Treatment

160 citations , March 2009 in “Seminars in Cutaneous Medicine and Surgery”

New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.

research A Histologic Review of 27 Patients with Lichen Planopilaris

76 citations , June 2008 in “Journal of the American Academy of Dermatology”

The conclusion is that certain scalp tissue changes are characteristic of lichen planopilaris, with mucinous perifollicular fibroplasia being a new feature for diagnosis.

research Onset of Lichen Planopilaris During Treatment with Etanercept

39 citations , March 2008 in “British Journal of Dermatology”

Etanercept may cause lichen planopilaris, so doctors should be cautious.

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Hair transplants can cause hair loss if done while lichen planopilaris is active; wait until it's inactive for two years and check with a scalp biopsy first.

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