TLDR Scalp lesions in discoid lupus are more common in women and linked to other autoimmune diseases.
This study analyzed 126 patients with discoid lupus erythematosus (DLE) to determine if scalp lesions had distinct clinical and serological characteristics compared to lesions in other locations. It was found that scalp lesions were more common in females, with women being up to 4.3 times more likely to have them. There was a significant difference in the positivity of antinuclear antibodies (FAN), with those without scalp lesions showing higher positivity. Additionally, patients with localized DLE who did not have scalp lesions were more likely to be smokers and have positive FAN. Scalp lesions were also more associated with other autoimmune diseases. The study highlighted that more than 60% of DLE patients had scalp involvement, with 1/3 experiencing scarring alopecia.
46 citations
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June 2018 in “American Journal of Clinical Dermatology” Hair loss is common in lupus patients and can be permanent or reversible, depending on the type, with various treatments available.
15 citations
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January 2014 in “Anais Brasileiros de Dermatologia” Lupus treatment requires a combination of drugs and therapies, with research needed for new options.
144 citations
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September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
18 citations
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March 2004 in “Clinics in Dermatology” Lupus can cause hair loss and nail changes, with treatments available for both.
254 citations
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December 2003 in “Journal of the American Academy of Dermatology” Accurate diagnosis and aggressive treatment are crucial to prevent permanent hair loss in cicatricial alopecia.
January 2023 in “Skin appendage disorders” Hair loss is common in autoimmune diseases and can be an early sign of the condition, often requiring prompt treatment to prevent permanent damage.
July 2018 in “Elsevier eBooks” Discoid Lupus Erythematosus often causes scarring hair loss, is influenced by genetics and environment, and requires early treatment to prevent worsening.
44 citations
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April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
1 citations
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June 2014 in “Serbian Journal of Dermatology and Venereology” A woman with discoid lupus improved with treatment after being misdiagnosed with a different hair loss condition.
2 citations
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January 2004 in “Elsevier eBooks” Lupus affects the skin in various ways, and proper skin examination is crucial for diagnosis and treatment.
