Epidemiology and Pathogenesis of Lichen Planopilaris in the Dermatology Clinic of Charité Berlin

    January 2013 in “ Refubium (Universitätsbibliothek der Freien Universität Berlin) ”
    Johanna Meinhard
    TLDR Lichen planopilaris is more common in older women and may be linked to hormone therapy and autoimmune diseases.
    The study focused on the epidemiology and pathogenesis of Lichen planopilaris (LPP), a scarring alopecia, by analyzing records of 104 patients treated at Charité Dermatology from January 2009 to March 2011. It identified 71 cases of classical LPP, 32 of frontal fibrosing alopecia (FFA), and one of Graham-Little-Picardi Syndrome. The study found that LPP was more common in older women, those with Fitzpatrick skin types I-III, and postmenopausal women, particularly those undergoing hormone replacement therapy. There was also a tendency for LPP to be associated with autoimmune diseases like Vitiligo, Alopecia areata, and thyroid disorders. The study highlighted the lack of standardized treatment guidelines for LPP and suggested the need for systematic data collection to support future research and therapy development.
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