January 2025 in “International journal of research studies in biosciences” This abstract discusses the prevalence and forms of lichen planopilaris, a type of scarring hair loss, but reports no new clinical findings.
July 2023 in “Dermatology Practical & Conceptual” This study found that a positive anagen pull test can be an indicator of lichen planopilaris activity, suggesting its utility in the clinical assessment of this condition.
1 citations
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May 2015 in “Journal of The American Academy of Dermatology” Lichen planus pigmentosus and fibrosing frontal alopecia in Colombia are likely different stages of the same disease.
90 citations
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July 2008 in “Dermatologic therapy” This article reviews lichen planopilaris, a chronic scarring alopecia, and explores recent treatment developments, but it reports no new clinical results.
April 2025 in “Health Science Reports” PRP treatment improved skin pigmentation and appearance in facial lichen planus pigmentosus.
11 citations
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February 2020 in “Dermatology and therapy” This study reported that four patients with lichen planopilaris showed dramatic improvement, including symptom reduction and hair regrowth, after treatment with low-level light therapy.
June 2026 in “British Journal of Dermatology” This case study documented the first known instance of biopsy-confirmed lichen planopilaris occurring after hairline-lowering surgery in a patient without prior history, highlighting a potential complication where surgical trauma may trigger immune-mediated hair loss.
47 citations
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June 2014 in “Journal of Dermatological Treatment” This retrospective review found that while intralesional corticosteroids provided symptomatic improvement for lichen planopilaris, hydroxychloroquine with topical corticosteroids led to higher remission rates but did not result in visible hair regrowth.
253 citations
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April 2009 in “Journal of Biological Chemistry” This study found that p2y5 functions as a novel LPA receptor involved in the G13-Rho signaling pathway, with implications for human hair growth, and proposes renaming it to LPA6.
June 2023 in “International Journal of Dermatology” This study reviewed 41 cases of lichen planus pigmentosus in patients from southeastern Tunisia, highlighting its prevalence among older individuals and notable differences compared to patterns observed in an Indian cohort.
June 2025 in “British Journal of Dermatology” This reported case of lichen planopilaris in siblings suggests a potential genetic predisposition, supporting the hypothesis of inherited susceptibility in this condition.
July 2021 in “Authorea (Authorea)” This article discusses Graham-Little Piccardi Lassueur Syndrome, a rare variant of Lichen planopilaris, but reports no clinical findings or results.
1 citations
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July 2022 in “PLOS ONE” This study found that in Lichen Planopilaris, the Microbacteriaceae family was negatively correlated with IL-23 expression, suggesting a role in the disease's inflammation and microbiota composition.
22 citations
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April 2011 in “Anais Brasileiros de Dermatologia” This report describes two cases where lichen planopilaris may have compromised the hair follicles in both donor and recipient areas following follicular unit transplantation.
14 citations
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January 2015 in “Skin appendage disorders” This study reports that subtle presentations of lichen planopilaris may be mistaken for seborrheic dermatitis in patients with androgenetic alopecia, highlighting the importance of dermatoscopy-guided biopsy for accurate diagnosis.
December 2024 in “Skin Appendage Disorders” This bibliometric analysis revealed important studies on LPP, noted essential trichoscopic features, and identified significant evidence gaps. The researchers emphasized a need for more robust and diverse studies to improve diagnostics and treatment strategies.
71 citations
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October 2017 in “Journal of Investigative Dermatology” PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
1 citations
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May 2022 in “Journal of Drugs in Dermatology” This case report describes a patient with lichen planopilaris who experienced remarkable hair regrowth at a previously scarred area after treatment with low-dose naltrexone and platelet-rich plasma, following minimal response to other therapies.
This study found that patients with lichen planopilaris exhibit a higher pro-atherogenic lipid profile and elevated atherogenic indexes, suggesting a need for increased cardiovascular and lipid monitoring in these individuals.
16 citations
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January 2019 in “Neuropsychobiology” This study found that individuals with lichen planopilaris reported lower quality of life and self-esteem and higher depression scores compared to healthy controls.
November 2024 in “Cureus” The authors reported a case of significant scalp edema accompanying lichen planopilaris in a middle-aged woman, suggesting a potential new variant of edematous scalp conditions as a reaction to scarring alopecia.
May 2014 in “Clinical and Experimental Dermatology” A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.
220 citations
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June 2013 in “The Journal of Pathology” This study found that immune privilege collapse in the hair follicle bulge and associated immune responses may contribute significantly to the pathogenesis of lichen planopilaris, suggesting a potential autoimmune basis for the disease.
49 citations
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January 2010 in “Plant and Cell Physiology” This study found that a phosphorus starvation-insensitive mutant of Arabidopsis thaliana shows altered root growth and auxin responses under low phosphate conditions compared to wild-type plants, suggesting a role for LPR1 in regulating these traits.
January 2025 in “Dermatology Research and Practice” In this research, RNA expression analysis of scalp biopsies from lichen planopilaris patients revealed changes in specific genes after treatments with hydroxychloroquine, narrow band UVB, or low level laser light therapy, suggesting potential biomarkers and implicating M2 macrophages in the disease's immunopathogenesis.
3 citations
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December 2024 in “Pediatric Dermatology” This review discusses the clinical and histopathologic features of pediatric lichen planopilaris and reports therapeutic responses to various treatments; the condition should be considered in cases of patchy hair loss in children.
In this case study, an 80-year-old woman developed lichen planus pigmentosus inversus after receiving multiple intra-articular injections of a homeopathic preparation, suggesting a possible link, though causality remains speculative.
44 citations
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February 2017 in “Journal of the American Academy of Dermatology” This study found that postmenopausal women with lichen planopilaris showed a high prevalence of androgen excess, while women with frontal fibrosing alopecia were often associated with androgen deficiency.
January 2022 in “Clinical Cases in Dermatology” This article discusses the causes and treatment options for lichen planopilaris, a scarring hair loss condition, but reports no new clinical findings.