April 2023 in “Journal of dermatological treatment” This study reports a case of complete hair regrowth in lichen planopilaris after 12 weeks of treatment with ixekizumab, suggesting its potential as a targeted therapy.
5 citations
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August 2001 in “International Journal of Dermatology” This case study reports a 20-year-old laborer's progressive hair loss with scalp and body lesions, diagnosed as lichen planopilaris, leading to scarring alopecia resembling male-pattern baldness.
March 2024 in “Case Reports in Dermatology” This report details a case where diffuse lichen planopilaris and female pattern hair loss in a 32-year-old woman mimicked diffuse alopecia areata, highlighting the diagnostic value of dermoscopy-guided biopsies and the importance of timely treatment to prevent disease progression.
January 2022 in “Clinical Cases in Dermatology” This article discusses the causes and treatment options for lichen planopilaris, a scarring hair loss condition, but reports no new clinical findings.
April 2023 in “Journal of Investigative Dermatology” In this study, the KPAI and KP-IGA scoring systems for assessing keratosis pilaris showed excellent interrater and intrarater reliability, offering standardized measures for clinical and research use.
May 2025 in “Frontiers in Genetics” This study reported discovering a novel missense variant in a case of autosomal recessive woolly hair in a 31-year-old Chinese woman, which significantly reduced secretion of the encoded protein, likely leading to disease by impairing its hydrolytic function.
January 2013 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” This study observed that hormone replacement therapy and autoimmune diseases may be more common among women with frontal fibrosing alopecia compared to those with androgenetic alopecia.
September 2024 in “Skin Research and Technology” This study used atomic force microscopy to identify significant morphological differences in hair from patients with lichen planopilaris compared to healthy controls, noting more scratches, uneven edges, and pitted scales in affected hair, which may aid future research on the condition.
44 citations
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June 2017 in “The EMBO Journal” This study reports that the autotaxin–LPA–LPA3 signaling pathway at the embryo-epithelial boundary plays a critical role in decidualization by up-regulating HB-EGF and COX-2 in the uterine epithelium.
October 2025 in “Our Dermatology Online” This study suggests that combining tranexamic acid with low-dose oral retinoids may offer moderate to good improvements for lichen plan pigmentosus, although larger trials are needed for confirmation.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that the loss of Langerhans cells in lichen planopilaris scars may be linked to the downregulation of ITG αvβ6, which is not seen in other scar formation diseases.
July 2017 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers investigated the role of the ATX-LPA axis in asthma pathogenesis using human and mouse models and highlighted the potential for developing new ATX inhibitors as effective asthma treatments.
October 2021 in “The Egyptian Journal of Hospital Medicine” In this study, intralesional platelet-rich plasma was found to be a beneficial and safe treatment option for oral lichen planus, an inflammatory disease affecting the oral mucosa.
5 citations
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April 2014 in “The American Journal of Dermatopathology” This article reports on a typical case of lichen planopilaris with foreign-body granulomas around hair shaft material, suggesting these may be an additional criterion for diagnosing late-stage LPP/FFA.
6 citations
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January 2016 in “Skin appendage disorders” This case report describes a 38-year-old male with scarring body hair loss as the sole manifestation of lichen planopilaris, characterized by progressive alopecia and preceding itching.
July 2021 in “Authorea (Authorea)” This article discusses Graham-Little Piccardi Lassueur Syndrome, a rare variant of Lichen planopilaris, but reports no clinical findings or results.
2 citations
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December 2013 in “Journal of dermatology” This letter reports a homozygous missense mutation in the LIPH gene causing autosomal recessive hypotrichosis simplex in a Chinese patient.
16 citations
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October 2014 in “Journal of the American Academy of Dermatology” This study found that oral retinoid therapy may provide clinical improvement in a small percentage of patients with treatment-resistant lichen planopilaris, although it is not commonly used as a first-line treatment.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that the expression and localization of toll-like receptors and caveolin-1 in lichen planopilaris may influence cicatricial alopecia pathobiology and that downregulating caveolae could offer a novel management strategy.
February 2023 in “Journal of dermatology” This letter reports the first known Japanese case of autosomal recessive woolly hair/hypotrichosis with compound heterozygous mutations in the LIPH gene.
151 citations
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August 2011 in “The EMBO Journal” The enzyme PA-PLA1α is important for proper hair follicle development.
1 citations
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January 2025 in “Proceedings of the National Academy of Sciences” This study used cryoelectron microscopy to unveil the structure of LPA-bound human LPAR6, revealing unique ligand binding and recognition modes distinct from LPAR1, which may aid in designing targeted compounds for hair loss and cancer.
6 citations
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August 2020 in “Clinical case reports” In this study, patients with facial papules due to Lichen planopilaris showed no improvement with treatments for frontal fibrosing alopecia or scalp Lichen planopilaris.
8 citations
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July 2020 in “Journal of The American Academy of Dermatology” Patients with Lichen Planopilaris are more likely to have rosacea and skin cancer but less likely to have congestive heart failure, stroke, and glaucoma.
January 2026 in “Case Reports in Dermatological Medicine” This report identified a family of Iranian siblings with diverse clinical forms of Lichen Planus, suggesting potential genetic and environmental involvement in its pathogenesis.
21 citations
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September 2018 in “International journal of women’s dermatology” In this study, patients with lichen planopilaris showed higher prevalence of autoimmune disorders like Hashimoto's thyroiditis and hypothyroidism compared to those with seborrheic dermatitis.
May 2025 in “International Medical Case Reports Journal” This case report highlights lichen planus pigmentosus in a 60-year-old man, which was linked to previously undetected hepatitis C infection and liver cirrhosis, suggesting a need for hepatitis C testing in patients with similar dermatological manifestations.
11 citations
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August 2010 in “Annals of plastic surgery” This study found a significant relationship between lash ptosis severity and marginal reflex distance, levator function, and double fold presence in Asian patients, which may inform surgical planning for upper eyelid procedures.
December 2023 in “Journal of General Procedural Dermatology and Venereology Indonesia” The abstract highlights that lichen planus can manifest as cicatricial alopecia or lichen planopilaris, while discoid lupus erythematosus, a common form of lupus erythematosus, typically causes scarring alopecia. Results are not reported here.
9 citations
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September 2018 in “JAAD Case Reports” This article describes a unique case of lichen planopilaris with a previously unreported trigger in one of the youngest documented adult patients, without providing new clinical results or data.