Successful Treatment of Rare Linear Lichen Planopilaris With Ixekizumab

April 2023 in “ Journal of dermatological treatment ”

Hanof Ahmed, Mahir Petkar, Martin Steinhoff

lichen planopilaris LLPP Ixekizumab anti-IL-17A/F antibody hair regrowth scalp forehead

TLDR Ixekizumab successfully treated a rare hair loss condition, leading to complete hair regrowth.

The document reports a case of successful treatment of a rare form of lichen planopilaris (LLPP) using Ixekizumab, an anti-IL-17A/F antibody. A 30-year-old woman with LLPP involving the scalp and forehead achieved complete hair regrowth within 12 weeks of treatment, with sustained efficacy and no side effects for 12 months. Previous treatments had failed to produce satisfactory results. This case suggests that Ixekizumab could be a viable first-line therapy for LPP and its variants, warranting further multicenter trials to confirm its benefits.

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