1 citations
,
July 2021 in “Curēus” This case report describes a rare occurrence of lichen planopilaris in a nine-year-old child, emphasizing the need for awareness of this condition in the pediatric population.
12 citations
,
June 2020 in “Journal of The American Academy of Dermatology” This article discusses platelet-rich plasma therapy for cicatricial alopecias like lichen planopilaris and reports no confirmed new clinical results; the authors highlight ongoing uncertainty about its effectiveness and potential risks.
1 citations
,
May 2022 in “Journal of Drugs in Dermatology” This case report describes a patient with lichen planopilaris who experienced remarkable hair regrowth at a previously scarred area after treatment with low-dose naltrexone and platelet-rich plasma, following minimal response to other therapies.
1 citations
,
May 2024 in “International Journal of Innovative Science and Research Technology (IJISRT)” This review analyzed recent studies and concluded that JAK inhibitors are effective for treating lichen planopilaris, though concerns about long-term safety remain and further research is needed.
June 2026 in “British Journal of Dermatology” This case study documented the first known instance of biopsy-confirmed lichen planopilaris occurring after hairline-lowering surgery in a patient without prior history, highlighting a potential complication where surgical trauma may trigger immune-mediated hair loss.
1 citations
,
May 2024 in “Cureus” This case series describes five patients with rare facial lichen planopilaris, detailing the clinical presentation and treatment of their pigmentary changes and scarring alopecia.
158 citations
,
June 2014 in “Journal of Lipid Research” This review summarizes recent discoveries of GPCRs for lysophosphatidylserine and lysophosphatidylinositol, detailing their roles as lipid mediators, but reports no new experimental results.
2 citations
,
October 2020 in “International Journal of Dermatology” This study found that lichen planopilaris in men typically presents similarly to women, with a lower likelihood of nonscalp hair loss and a higher association with mucosal lichen planus and thyroid disease.
This report describes two cases where lichen planopilaris compromised hair follicles in both donor and recipient areas after follicular unit transplantation, emphasizing the need for a biopsy if lichen planopilaris is suspected.
3 citations
,
December 2024 in “Pediatric Dermatology” This review discusses the clinical and histopathologic features of pediatric lichen planopilaris and reports therapeutic responses to various treatments; the condition should be considered in cases of patchy hair loss in children.
2 citations
,
September 2025 in “Future Journal of Pharmaceutical Sciences” This study reviewed the potential of Lupeol, a natural triterpenoid, in promoting hair growth and reducing inflammation related to alopecia, revealing promising molecular pathways and favorable pharmacokinetics while suggesting further research to validate these findings.
January 2026 in “Forum Dermatologicum” This study reviewed cases of Graham–Little-Piccardi–Lassueur syndrome and found that topical treatments were generally ineffective, while systemic therapies like prednisone, hydroxychloroquine, and isotretinoin led to partial hair regrowth and disease stabilization, highlighting the importance of early diagnosis and systemic therapy to improve outcomes.
In this study, PDLLA treatment in middle-aged mice was observed to enhance hair growth by increasing macrophage M2 polarization and hair follicle stem cell proliferation, potentially rejuvenating the skin's microenvironment and offering a novel approach for age-related hair loss.
2 citations
,
June 2016 in “Oral Surgery Oral Medicine Oral Pathology and Oral Radiology” This study reports the first known case of oral lichen planus preceding lichen planopilaris in a patient, highlighting a possible sequential relationship between the conditions.
47 citations
,
June 2014 in “Journal of Dermatological Treatment” This retrospective review found that while intralesional corticosteroids provided symptomatic improvement for lichen planopilaris, hydroxychloroquine with topical corticosteroids led to higher remission rates but did not result in visible hair regrowth.
44 citations
,
February 2017 in “Journal of the American Academy of Dermatology” This study found that postmenopausal women with lichen planopilaris showed a high prevalence of androgen excess, while women with frontal fibrosing alopecia were often associated with androgen deficiency.
1 citations
,
November 2024 in “Cutis” PLLA injections can cause hair loss and skin issues.
December 2024 in “Skin Appendage Disorders” This bibliometric analysis revealed important studies on LPP, noted essential trichoscopic features, and identified significant evidence gaps. The researchers emphasized a need for more robust and diverse studies to improve diagnostics and treatment strategies.
May 2014 in “Clinical and Experimental Dermatology” A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.
This study conducted a comparative analysis of platelet rich plasma and low level laser therapy for androgenetic alopecia but does not present new clinical findings.
22 citations
,
April 2013 in “International Journal of Dermatology” Frontal fibrosing alopecia can occur with lichen planus pigmentosus, needing careful diagnosis and treatment.
January 2015 in “Hair transplant forum international” Up to 10% of hair loss patients might have early signs of a condition called Lichen Planopilaris.
February 2023 in “Journal of Ginseng Research/Journal of ginseng research” This review discusses the formation of gintonin LPAs in ginseng during processing and reports no new clinical results; the authors suggest potential benefits against degenerative diseases through LPA receptors.
April 2012 in “The FASEB Journal” In this study, researchers observed that knocking down the LPA 4 receptor in zebrafish embryos led to vascular and lymph vessel development abnormalities, including edema and decreased heartbeats.
24 citations
,
December 2018 in “Inflammation and Regeneration” This review discusses the roles of various PLA2 enzymes in skin health and disease, highlighting potential pathways for future diagnosis and therapy, but it reports no new clinical results.
1 citations
,
September 2013 in “The Journal of Dermatology” An 8-year-old girl developed a rare skin condition in a linear pattern on one side of her body after a lung infection, which improved with treatment.
58 citations
,
January 2015 in “Journal of the American Academy of Dermatology” Pioglitazone may help treat lichen planopilaris, but more research is needed.
38 citations
,
January 2017 in “PPAR Research” This review discusses the role of PPAR-γ in the pathogenesis of primary cicatricial alopecia, including its involvement in lichen planopilaris and treatment trials using PPAR-agonists, and reports no new clinical results.
4 citations
,
May 2020 in “Journal of The American Academy of Dermatology” This letter argues that cicatricial pattern hair loss likely represents end-stage androgenetic alopecia and not a variant of lichen planopilaris, as previously suggested.
June 2026 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This study concluded that oral tofacitinib significantly improved symptoms in patients with lichen planus pigmentosus who did not respond to conventional treatments, showing it as a viable alternative.