Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study concluded that the expression of clock genes, specifically BMAL1, in hair follicles is linked to circadian rhythm, and BMAL1 regulates hair growth.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

This study found that Shh from neurons signals to Gli1-expressing cells in the hair follicle, cultivating a niche where these bulge cells can potentially transform into epidermal stem cells in wound healing.

This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.

This review discusses the advancements in intraoperative stem cell therapies and highlights their potential to improve hair regrowth, but it reports no new clinical results.

This review discusses the development and advances in studying trichogenic dermal cells for hair follicle morphogenesis, summarizing methods, bioassays, and molecular markers, but reports no new research findings.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

This study found that Carthamus tinctorius exhibited the strongest 5α-reductase inhibitory and hair growth promoting activities among evaluated Thai herbs, suggesting potential for developing alternative hair loss treatments.

This study identified a sulfotransferase activity in rat liver that catalyzes the sulfation of minoxidil, contributing to its delayed hypotensive effects.

This study suggests that human and mouse hair follicle stem cells may support nerve repair and provide a practical source of stem cells for neurological therapies.

This study identified specific markers that can distinguish between stem cells in different regions of human scalp hair follicles, offering potential strategies for cell sorting and purification based on these markers.

Finasteride affects prostate weights and pituitary activity differently with age.

This study found that ethanolic leaves extract of Hibiscus rosa-sinensis L. exhibited strong antioxidant activity and enhanced wound healing properties in mice, showing reasonable safety in toxicological evaluations without severe alterations.

In this study, researchers reported that CD34 expression in the isthmic region of canine hair follicles suggests a potential stem cell compartment in this area.

This study found that neural stem cell extract enhanced hair growth in mice and cells by stimulating hair follicle niches and activating signaling pathways like TGF-β and BMP.

This study found that the pH dependency of rat steroid 5α-reductase type II isozyme significantly affects its kinetic properties, including Vmax and Km, suggesting past discrepancies in literature may arise from these pH variances during assays.

In this study, clozapine reduced suicide-related behaviors in a schizophrenia-like mouse model, but its effects on exploratory behavior were counteracted by the neurosteroid inhibitor finasteride.

This study found that Bacillus/Trapa japonica fruit ferment filtrate extracts enhanced human hair follicle dermal papilla cell proliferation through the Akt/ERK/GSK-3β signaling pathway, suggesting potential benefits for alopecia treatment.

This study found that several local vegetables from Northern Thailand demonstrated significant antioxidant and 5α-reductase inhibitory activities, suggesting their potential for development into health-promoting products.

This study found that treatment with the pure antiandrogen Flutamide did not affect the estrous cycle or plasma levels of most hormones in female rats, supporting its potential use for treating hirsutism, acne, and alopecia in women.

This study found that Thy1+ keratinocytes in the basal layer of the interfollicular epidermis play a crucial role in epidermal homeostasis and wound repair, with their ablation impairing these processes.

A boy with toxic shock syndrome had severe heart rhythm problems but recovered with treatment.

This article reviews the role of KLF4, a transcription factor, in various cellular processes and its dual function as a tumor suppressor or oncogene depending on the context, but presents no new experimental results.

This study found that the transcriptome of skin stem cells in mice changes significantly with age, revealing specific age-dependent biological programs and transcriptional hubs.

This study reports that a 30% ethanol extract of a plant mixture enhanced hair growth in human hair dermal papilla cells and mice, suggesting potential use in hair growth products.

This study developed a reliable RP-HPLC-DAD method, finding that amino acid concentrations in bleached hair decrease with higher hydrogen peroxide levels, notably affecting cystine.

This review discusses melanocyte stem cells in hair follicles and their potential role in cell-based therapy for vitiligo, reporting no new experimental results.

Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.

This study reported that molecules from Zebrafish embryo cell differentiation can counteract neurodegeneration, regenerate tissues, and potentially reverse hair follicle damage in androgenetic alopecia.

This study reported that a specific mixing ratio of Dendropanax extract and sea salt showed low cytotoxicity, high cell proliferation, anti-inflammatory, and antimicrobial effects, suggesting potential for functional cosmetics against hair loss.