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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Some traditional Chinese medicines may have anti-aging benefits and could help with hair growth, but more research is needed.

Many men misuse oral contraceptive pills for things like hair growth and muscle gain.

Gut health affects skin diseases, and probiotics might help.

Sugars from Sargassum and brown algae may have health benefits like fighting viruses and helping with wound healing, but there are challenges in using them.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.

Chemical hair straighteners can cause scalp and hair damage, but long-term effects are unclear.

The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.

Hemp is a promising ingredient for skin products due to its healing and soothing properties.

Hormonal imbalances during menopause may significantly contribute to Frontal Fibrosing Alopecia.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

Hair follicle stem cells can help treat ulcerative colitis in mice by releasing beneficial exosomes.

Finasteride may help treat kidney disease caused by a high-fat diet by reducing harmful toxins and improving gut bacteria.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.

Probiotics help reduce hair loss and increase hair growth in people with androgenic alopecia.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

Bimatoprost helps with hair growth and eye conditions but can be costly and have side effects.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Different types of PCOS need specific diagnosis methods and treatments.

Pinus densiflora extract may help improve memory and reduce brain inflammation.

Experts recommend personalized treatment plans for best outcomes in managing Alopecia Areata.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

Different genes cause Female Pattern Hair Loss compared to male hair loss, and treatments vary, but more research is needed to understand it fully.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.