172 citations,
November 1983 in “Journal of The American Academy of Dermatology” Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.
12 citations,
June 2019 in “Psychoneuroendocrinology” Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.
13 citations,
January 2020 in “Neuroscience” Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
11 citations,
August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
104 citations,
May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
31 citations,
April 2019 in “Cell reports” Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
7 citations,
April 2011 in “Expert review of dermatology” The document concludes that patients with skin of color need specialized dermatological care and education to manage unique skin conditions effectively.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
506 citations,
January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
75 citations,
January 2014 in “Archiv Der Pharmazie” Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.
38 citations,
December 2009 in “Therapeutic Advances in Medical Oncology” The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
3 citations,
October 2010 in “Epilepsy Currents” Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.
2 citations,
October 2022 in “International journal of Ayurvedic medicine” Licorice has many traditional health benefits, but more research is needed to fully support these claims.
40 citations,
December 2012 in “Epilepsia” Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
38 citations,
March 2017 in “Expert Opinion on Investigational Drugs” Bimatoprost is promising for treating some types of hair loss but needs more testing for androgenetic alopecia.
44 citations,
July 2012 in “Endocrine Practice” We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.
32 citations,
December 2019 in “The Journal of clinical investigation/The journal of clinical investigation” A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
3 citations,
February 2023 in “International Journal of Molecular Sciences” Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.
May 2024 in “European Journal of Immunology” Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.
January 2023 in “Skin appendage disorders” Low-dose oral minoxidil may help treat hair loss but is not FDA-approved and can cause side effects like unwanted hair growth and heart issues.
November 2012 in “Endocrine Practice” Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.
21 citations,
January 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
November 2020 in “Psychoneuroendocrinology” Finasteride might affect memory by impacting cholinergic system.
151 citations,
July 2011 in “Archives of Dermatological Research” Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
72 citations,
December 2012 in “Expert Opinion on Drug Delivery” Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
10 citations,
May 2021 in “Expert Opinion on Drug Delivery” Coenzyme Q10 vesicular formulations can potentially treat androgenic alopecia by promoting hair growth and thickness.
159 citations,
July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
137 citations,
March 2006 in “Cns Drug Reviews” Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
43 citations,
February 2020 in “Clinica chimica acta” Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
30 citations,
January 2000 in “Dermatologic Clinics” Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.