8 citations
,
January 2022 in “Journal of Experimental Orthopaedics” This scoping review explores devices that mechanically process lipoaspirate for cell-based therapies but finds insufficient evidence to determine their clinical effectiveness due to lack of standardization and data variability.
2 citations
,
March 2019 in “Plastic and Reconstructive Surgery” This review discusses various mechanical isolation procedures for tissue-like stromal vascular fraction, such as the nanofat procedure, and highlights the need for controlled trials to assess their regenerative effectiveness.
The study found that adipose-derived mesenchymal stem cells obtained via laser-assisted liposuction with selective photo-stimulation are comparable in differentiation potential and tumorigenic risk to those from conventional liposuction for cell therapy applications.
132 citations
,
January 2017 in “International Journal of Molecular Sciences” This review explores how adipose-derived stem cells contribute to skin homeostasis and highlights recent advances in their clinical applications in dermatology, but it reports no new clinical results.
October 2021 in “QJM: An International Journal of Medicine” This study found that injection of adipose-derived adult stem cells improved hair density, thickness, and reduced inflammation in women with female pattern hair loss over 24 weeks.
1 citations
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September 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this case report, researchers observed that scalp injection of adipose tissue may have a positive effect on hair regrowth in a patient with trauma-induced alopecia.
39 citations
,
March 2009 in “Clinics in plastic surgery” This review discusses the evolution and studies of injection lipolysis for fat reduction, highlighting the need for more research to ensure patient safety and treatment efficacy; it reports no new clinical results.
2 citations
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September 2011 in “InTech eBooks” This article describes a procedure involving skin marking, tumescent anesthesia, and micrograft mobilization, but does not present any study findings or results.
April 2023 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study concluded that mesenchymal stem cells from adipose tissue harvested using laser-assisted liposuction with selective photo-stimulation are as effective and low-risk for cell therapy as those obtained through conventional liposuction, based on their differentiation potential, cellular proliferation, and cytokine expression.
April 2023 in “Journal of Investigative Dermatology” In this single-center study, small-volume tumescent liposuction resulted in significant reductions in waist and hip circumferences but did not show significant improvements in metabolic markers.
316 citations
,
June 2017 in “Stem Cell Research & Therapy” This review covers the potential of SVF and ADSC therapies in regenerative medicine and highlights the challenges of regulation and efficacy, without reporting new clinical results.
43 citations
,
June 2016 in “Clinics in Plastic Surgery” This article reviews technical aspects of using autologous fat transfer for facial rejuvenation and examines existing evidence for stem cell and platelet-rich plasma therapies in aesthetic practice, reporting no new results.
14 citations
,
October 2012 in “Clinics in Plastic Surgery” Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.
1 citations
,
January 2013 in “Archives of Aesthetic Plastic Surgery” This study found that combining liposuction with diode laser ablation was effective in treating axillary osmidrosis, with high patient satisfaction and no significant complications reported over a 10-month follow-up period.
9 citations
,
October 2012 Tumescent local anesthesia is a safe, cost-effective method for outpatient liposuction.
45 citations
,
May 2018 in “Stem Cell Research & Therapy” In this study, patients receiving adipose-derived stromal vascular cell transplantation for alopecia areata experienced significant hair regeneration, increased growth, and improved hair quality after 3 and 6 months, indicating potential efficacy of this stem cell-based therapy for hair loss.
42 citations
,
February 2018 in “International Journal of Molecular Sciences” This study suggests that minoxidil may enhance hair growth by stimulating adipose-derived stem cell motility and growth factor secretion, promoting dermal papilla cell proliferation and accelerating anagen induction.
42 citations
,
February 2014 in “Stem Cells and Development” This study found that vitamin C increased the survival, proliferation, and hair-regenerative potential of adipose-derived stem cells through the MAPK pathway and enhanced hair growth in mice.
19 citations
,
January 2017 in “Stem Cells International” This review discusses the potential of adipose-derived stem cells for treating vitiligo, hair loss, and chronic wound healing, but reports no new clinical results and suggests the need for further investigation.
14 citations
,
May 2019 in “Experimental Dermatology” In this study, adipose tissue secretome was shown to enhance oxidative stress resistance and promote cell proliferation in vitiligo cells, suggesting a potential natural treatment approach.
9 citations
,
September 2019 in “Clinical, Cosmetic and Investigational Dermatology” In this case report, the authors observed that scalp injection of autologous adipose tissue had a positive effect on hair growth in a patient with trauma-related alopecia, suggesting it might be a promising treatment for alopecia.
6 citations
,
June 2018 in “Journal of Stomatology, Oral and Maxillofacial Surgery” In this cadaveric study, lipofilling was found easier to perform on the face than the scalp, whereas nanofat grafting was particularly suited for precise injections in scalp areas, suggesting a combination of techniques could aid in treating alopecia.
4 citations
,
September 2020 in “Annals of Translational Medicine” This study found that concentrated nanofat, used alone or with decellularized nanofat, may enhance hair growth in mice by activating dermal papilla cells and the anagen phase.
1 citations
,
January 2014 in “Journal of Cutaneous and Aesthetic Surgery” Regenerative medicine shows promise for aesthetic surgery, but needs more research for widespread use.
January 2023 in “Postępy Dermatologii i Alergologii” This review discusses the clinical applications of adipose tissue-derived stem cells in dermatology and plastic surgery, highlighting their potential benefits but also noting existing limitations and concerns.
August 2004 in “Journal of the American College of Surgeons” This study found that endothelial cells under serum deprivation significantly upregulated genes related to inflammation and coagulation, which may impact outcomes in tissue transfer procedures.
April 2021 in “Journal of Cosmetic Dermatology” Stem cell treatment improved hair density in female hair loss patient.
3 citations
,
December 2020 in “Journal of Cosmetic Dermatology” This study reported that autologous whole fat injection in the scalp considerably increased hair growth in patients with androgenetic alopecia.
January 2025 in “Aesthetic Surgery Journal Open Forum” This study investigated a fat grafting technique (MID BACK) to enhance back muscle definition in patients undergoing liposculpture, reporting no adverse events and only minor complications, suggesting the method is safe and effective for improving muscular contours and correcting spinal asymmetries.
30 citations
,
May 2008 in “International Journal of Dermatology” This case report describes a 52-year-old black woman with diffuse scalp swelling and thinning hair attributed to a large increase in the thickness of scalp subcutaneous fatty tissue.