January 2026 in “Dermatology Practical & Conceptual” This study reported that diffuse lichen planopilaris significantly impairs quality of life in Moroccan patients, with trichodynia and hair quality changes most affecting daily functioning and leisure activities.
April 2023 in “Journal of dermatological treatment” This study reports a case of complete hair regrowth in lichen planopilaris after 12 weeks of treatment with ixekizumab, suggesting its potential as a targeted therapy.
March 2026 in “Folia Histochemica et Cytobiologica” This review highlights LTBP1 as a critical integrator in disease processes, showing its dual role in cancer progression and suppression, its pathological influence in fibrosis, and its contribution to various disorders, suggesting its potential as a biomarker and therapeutic target.
September 2016 in “Ege tıp dergisi/Ege tıp dergisi :” In this case report, an 11-year-old girl was diagnosed with lipedematous scalp, a condition typically observed in adult women, based on clinical features and histopathological findings.
6 citations
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January 2013 in “Journal of Cosmetics Dermatological Sciences and Applications” This study found that lichen planopilaris is a common cause of scalp scarring alopecia in adults and has distinctive clinical features that help differentiate it from other similar conditions.
April 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study identified 64 chemical compounds in the L. luteus L. plant, including several fatty acids and coumarin, highlighting the pharmacognostic potential of yellow lupine.
90 citations
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July 2008 in “Dermatologic therapy” This article reviews lichen planopilaris, a chronic scarring alopecia, and explores recent treatment developments, but it reports no new clinical results.
3 citations
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August 2024 in “Molecular Biology Reports” This study found that the lncRNA018392, responsive to melatonin, accelerates cell proliferation in cashmere goats by recruiting the transcription factor SPI1 to upregulate the nearby gene CSF1R, which may explain the molecular mechanisms of cashmere growth.
1 citations
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April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that oral tofacitinib improved disease activity in patients with lichen planopilaris, suggesting it may be a promising treatment option for this condition.
2 citations
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October 2022 in “Dermatologic Therapy” Results are not reported in this article by Zizhuo Li et al. on baricitinib as a treatment for lichen planopilaris.
3 citations
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March 2015 in “Biomolecules & Therapeutics” In this study, BP201, derived from porcine lung phospholipids, promoted hair growth in mice, especially when combined with minoxidil, and increased hair follicle numbers and dermal papilla cell proliferation.
June 2001 in “Proceedings of SPIE” The authors concluded that low energy laser therapy may serve as a useful complementary treatment for skin diseases such as lichen planus, infectious finger pulpits, scalp alopecia, and crural ulcers.
July 2025 in “Human Genomics” This source reports that a comprehensive review of LSS gene variant phenotypes enhances understanding of congenital hypotrichosis 14 and could guide more precise genetic counseling and future research into disease mechanisms and potential therapies.
151 citations
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July 2011 in “Archives of Dermatological Research” This review discusses various strategies to enhance drug delivery through the skin barrier, highlighting liposomes as promising carriers for increased dermal concentrations in topical therapies, but reports no new research results.
October 2010 in “한국식품영양과학회 산업심포지움발표집” Fermented Liriope platyphylla helps hair grow in mice with hair loss.
February 2023 in “Journal of Ginseng Research/Journal of ginseng research” This review discusses the formation of gintonin LPAs in ginseng during processing and reports no new clinical results; the authors suggest potential benefits against degenerative diseases through LPA receptors.
1 citations
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April 2024 in “Plastic & Reconstructive Surgery Global Open” This study found that using a blunt cannula for lip augmentation is a safe and effective alternative to traditional needle methods, resulting in no bruising and high patient satisfaction, which may influence future cosmetic practices.
In this case report, a 65-year-old woman with lichen planopilaris achieved stabilization of her condition through early recognition and systemic corticosteroid therapy, emphasizing the critical role of coordinated management between primary care and dermatology.
50 citations
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February 2016 in “Journal of Investigative Dermatology” A mutation in the KRT25 gene causes a rare hair disorder with thin, woolly hair.
39 citations
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December 2012 in “The American Journal of Human Genetics” This study identified mutations in the SNRPE gene that may disrupt hair growth, linking a spliceosome component to hereditary hair loss disorders.
35 citations
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January 2011 in “Journal of Biological Chemistry” This study found that overexpression of sPLA2-X in mice was associated with alopecia and hair follicle abnormalities, highlighting its potential role in hair follicle homeostasis.
9 citations
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July 2016 in “Genes” This study identified specific genetic variants as the cause of visual impairment and non-syndromic alopecia in two brothers, reinforcing the link between PDE6H variants and achromatopsia and LPAR6 variants and alopecia.
January 2025 in “Kuwait Journal of Science” In this study, researchers sequenced the KRT71 gene in 102 dromedary camels to find genetic polymorphisms linked to hair shape, identifying 17 variants but none that fully explained hair shape variations, suggesting other genes may also play a role.
In this study, researchers created a mouse model using CRISPR/Cas9 technology to investigate hypotrichosis simplex and woolly hair, finding that Krt71-knockout mice exhibited curly hair and developed complete hair shedding without immune deficiencies, mimicking conditions seen in humans and potentially aiding future hair disorder research.
May 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A mutation in the KRT74 gene causes woolly hair by affecting hair texture.
May 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A mutation in the KRT74 gene causes woolly hair by affecting hair texture.
April 2018 in “Journal of Investigative Dermatology” This study suggests that macrophages play a more substantial role in the pathogenesis of Lichen planopilaris compared to Frontal fibrosing alopecia, as indicated by increased CD68+ cells in Lichen planopilaris.
110 citations
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January 2014 in “Journal of Controlled Release” Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.
3 citations
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May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified loss of function variants in the HR gene as likely causes of the distinct roaning hair coat seen in lykoi cats.
79 citations
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September 2018 in “Dermatologic therapy” This study found that treatment with oral tofacitinib, alone or with other therapies, was associated with clinical improvement in most patients with recalcitrant lichen planopilaris.