23 citations
,
February 2020 in “PLOS genetics” This study found that biallelic LSS mutations lead to congenital hypotrichosis and cataracts, with each tissue-specific loss of function observed in mouse models.
February 2016 in “Acta Medica Marisiensis” This case study presents what is reportedly the first association of Graham Little-Lassueur Syndrome with chronic hepatitis C, observed in a 47-year-old female patient.
13 citations
,
November 2022 in “Biomaterials Science” This study demonstrated that a device combining hyaluronic acid-based dissolving microneedles and lipid polymer hybrid nanoparticles effectively delivered miR-218 to promote hair growth in a shaved mouse model, outperforming topical smear treatment without safety concerns.
24 citations
,
December 2018 in “Inflammation and Regeneration” This review discusses the roles of various PLA2 enzymes in skin health and disease, highlighting potential pathways for future diagnosis and therapy, but it reports no new clinical results.
1 citations
,
May 2024 in “Skin Appendage Disorders” This article discusses the importance of early recognition of LPP due to its significant aesthetic and psychosocial effects and calls for efforts to prevent misdiagnosis.
27 citations
,
June 2020 in “Genes” This study identified multiple loss of function variants in the HR gene linked to the unique hair coat phenotype in lykoi cats, also known as werewolf cats.
161 citations
,
April 2006 in “Journal of Investigative Dermatology” Liposomes with certain properties can effectively deliver drugs deep into hair follicles.
10 citations
,
May 2020 in “Dermatologic therapy” In this study, a patient with recalcitrant lichen planopilaris and frontal fibrosing alopecia showed significant improvement after receiving four doses of the interleukin-23 monoclonal antibody tildrakizumab.
3 citations
,
July 2025 in “International Immunopharmacology”
1 citations
,
July 2021 in “Curēus” This case report describes a rare occurrence of lichen planopilaris in a nine-year-old child, emphasizing the need for awareness of this condition in the pediatric population.
January 2025 in “International journal of research studies in biosciences” This abstract discusses the prevalence and forms of lichen planopilaris, a type of scarring hair loss, but reports no new clinical findings.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study examined clinical characteristics of lichen planopilaris and frontal fibrosing alopecia in 24 men, revealing common scalp symptoms, frequent beard involvement, and limited association with thyroid disease.
160 citations
,
March 2009 in “Seminars in Cutaneous Medicine and Surgery” This article reviews lichen planopilaris, its presentation, and treatment challenges, and emphasizes the need for more research into its pathogenesis and therapy efficacy; it reports no new findings.
24 citations
,
July 2015 in “Molecular Medicine Reports” This study found that lysophosphatidic acid increases mesenchymal stem cell proliferation and migration through signaling pathways and reactive oxygen species, implicating potential applications in stem cell expansion.
July 2023 in “Dermatology Practical & Conceptual” This study found that a positive anagen pull test can be an indicator of lichen planopilaris activity, suggesting its utility in the clinical assessment of this condition.
559 citations
,
October 2020 in “Frontiers in Molecular Biosciences” This review reports on the current state and potential of solid lipid nanoparticles for drug delivery, emphasizing their safety, biocompatibility, and ease of production, and highlights challenges in translating them to clinical practice, including active clinical trials.
35 citations
,
October 2015 in “International Journal of Pharmaceutics” Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.
April 2026 in “American Journal of Dermatopathology” This study identified a new dermoscopic feature, plexiform erythema, in lichen planopilaris lesions, suggesting it may indicate active disease and the potential need for more aggressive treatment.
13 citations
,
May 2021 in “Plants” This study found that the n-hexane fraction from Leea indica leaves significantly increased hair growth in mice and showed potential as a natural treatment for alopecia.
19 citations
,
July 2017 in “Clinical and experimental dermatology” This study provides one of the first descriptions of the demographic, clinical, and therapeutic characteristics of lichen planopilaris in Chilean adults, reporting that treatment usually reduced or halted disease progression.
6 citations
,
June 2013 in “International Journal of Cosmetic Science” This article is a letter to the editor discussing lipid distribution and its influence on hair structure and does not present any new research findings.
1 citations
,
June 2024 in “British Journal of Dermatology” In this case study, a woman with frontal fibrosing alopecia and associated hyperpigmentation showed significant improvement in skin pigmentation and itch after 9 months of treatment with mycophenolate mofetil, highlighting its therapeutic potential for lichen planus pigmentosus linked to this condition.
35 citations
,
February 2003 in “Biochimica et Biophysica Acta (BBA) - General Subjects” This study found that lead treatment enhances the imaging of organized hair lipid structures, revealing their orientation and possible composition as lead and calcium soaps, with potential applications in various fields.
June 2023 in “Journal of dermatology for physician assistants” This case report highlights a misdiagnosis of traction alopecia that progressed to lichen planopilaris in a patient of color, emphasizing the need to consider LPP in similar cases due to differing treatments.
July 2022 in “Journal of Investigative Dermatology” This study found that the transcription factor Lef1 is crucial for normal skin and hair development and wound healing, highlighting its role in regulating essential genes and pathways in papillary fibroblasts.
January 2018 in “Stem cell biology and regenerative medicine” This review discusses how the nuclear lamina integrates biochemical and mechanical signals to influence gene expression and skin homeostasis, but reports no new clinical results.
November 2023 in “The actual problems in dentistry” This review of 48 scientific sources identifies various treatment methods, including drug and non-drug approaches, for oral lichen planus, highlighting side effects and emphasizing the need for more effective and personalized treatments due to existing contraindications, especially in severe cases.
4 citations
,
May 2024 in “Cytotechnology”
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, treatment with oral JAK inhibitors was associated with improved disease outcomes in 80.6% of patients with refractory lichen planopilaris over a mean duration of 5 months.
19 citations
,
December 2015 in “Journal of Materials Chemistry B” This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.