Graham Little-Lassueur Syndrome with Hypertrophic Lichen Planus in a Patient with Chronic Hepatitis C
February 2016
in “
Acta Medica Marisiensis
”
TLDR A woman with chronic hepatitis C had a rare skin condition linked to her illness.
Graham Little-Lassueur Syndrome (GLLS) was reported in a 47-year-old female with chronic hepatitis C, poorly managed due to Interferon intolerance. She exhibited intensely pruritic erythematous plaques on her shins and cicatricial alopecia on her scalp. A skin biopsy confirmed hypertrophic lichen planus on the shins and lichen planopilaris on the scalp. Treatment included systemic antihistamines, topical corticosteroids, salicylic acid, emollients, UVB phototherapy, and cryotherapy. This case was notable as the first reported instance of GLLS associated with chronic hepatitis C.
